TY - JOUR AU - Castañeyra-Perdomo, A. AU - Meyer, G. AU - Carmona-Calero, E. AU - Perez-Gonzalez, H. AU - Del Mar Perez-Delgado, M. AU - Bañuelos-Pineda, J. AU - Ferres-Torres, R. T1 - The effects of chronic administration of captopril on the mouse subfornical organ and area postrema LA - eng PY - 1993 SP - 145 EP - 148 T2 - Experimental Neurology SN - 0014-4886 VL - 120 IS - 1 AB - We have studied by morphometric procedures the chronic effect of captopril on the subfornical organ (SFO) and area postrema (AP) of the adult mouse. Oral administration of captopril does not produce any change in the size of individual nuclei of the ependymocytes and neurons in both centers. However, there are other quantitative effects of captopril on the global volume of the SFO and on the neuropil and vascular elements of both the SFO and AP which present a significant increase. It is suggested that this increase is due to metabolic processes at the level of both circumventricular organs. © 1993 Academic press, Inc. DO - 10.1006/exnr.1993.1048 UR - https://portalciencia.ull.es/documentos/5e39b7702999523aa927132b DP - Dialnet - Portal de la Investigación ER -