TY  - JOUR
AU  - Herrera-Herrera, A.V.
AU  - Ravelo-Pérez, L.M.
AU  - Hernández-Borges, J.
AU  - Afonso, M.M.
AU  - Palenzuela, J.A.
AU  - Rodríguez-Delgado, M.Á.
T1  - Oxidized multi-walled carbon nanotubes for the dispersive solid-phase extraction of quinolone antibiotics from water samples using capillary electrophoresis and large volume sample stacking with polarity switching
LA  - eng
PY  - 2011
SP  - 5352
EP  - 5361
T2  - Journal of Chromatography A
SN  - 0021-9673
VL  - 1218
IS  - 31
AB  - In this work, a new method for the determination of eleven quinolone antibiotics (moxifloxacin, lomefloxacin, danofloxacin, ciprofloxacin, levofloxacin, marbofloxacin, enrofloxacin, difloxacin, pefloxacin, oxolinic acid and flumequine) in different water samples using dispersive solid-phase extraction (dSPE) and capillary zone electrophoresis with diode-array detection was developed. Oxidized multi-walled carbon nanotubes (o-MWCNTs) were used for the first time as stationary phases for the off-line preconcentration by dSPE of the antibiotics. A 65. mM phosphate buffer at pH 8.5 was found adequate for analyte separation while large volume sample stacking with polarity switching of the analytes dissolved in water containing 10% (v/v) of acetonitrile was carried out in order to improve the sensitivity. dSPE parameters, such as sample volume and pH, o-MWCNT amount, volume and type of eluent in dSPE were optimized. Application of the developed method to the analysis of spiked Milli-Q, mineral, tap, and wastewater samples resulted in good recoveries values ranging from 62.3 to 116% with relative standard deviation values lower than 7.7% in all cases. Limits of detection were in the range of 28-94. ng/L. The proposed method is very fast, simple, repeatable, accurate and highly selective. © 2011 Elsevier B.V.
DO  - 10.1016/j.chroma.2011.06.031
UR  - https://portalciencia.ull.es/documentos/5e3c366729995246bbf5dedc
DP  - Dialnet - Portal de la Investigación
ER  -