Retinopatía MEKCasos clínicos

  1. Pedro Rocha Cabrera 1
  2. E. Quijada Fumero 1
  3. M. J. Losada Castillo 1
  4. J. A. Abreu Reyes 1
  5. Jacob Lorenzo Morales 1
  1. 1 Hospital Universitario de Canarias
    info

    Hospital Universitario de Canarias

    San Cristóbal de La Laguna, España

    GRID grid.411220.4

Revista:
Archivos de la Sociedad Española de Oftalmologia

ISSN: 0365-6691

Ano de publicación: 2018

Volume: 93

Número: 1

Páxinas: 42-46

Tipo: Artigo

Exportar: RIS
DOI: 10.1016/j.oftal.2017.03.005 DIALNET GOOGLE SCHOLAR

Indicadores

Citas recibidas

  • Citas en Scopus: 1 (24-10-2021)

SCImago Journal Rank

  • Ano 2018
  • Impacto SJR da revista: 0.23
  • Cuartil maior: Q3
  • Área: Ophthalmology Cuartil: Q3 Posición na área: 90/126

CiteScore

  • Ano 2018
  • CiteScore da revista: 0.6
  • Área: Ophthalmology Percentil: 22

Resumo

Case reports: Three clinical cases are presented of MEK retinopathy associated with the combination of cobimetinib and vemurafenib characterised by alteration of the retinal pigment epithelium and neurosensory detachment. Two of the cases conserved the vision of the unit, and the third developed a large bilateral neurosensory detachment with final visual acuity of 0.6 for the right eye and 0.1 for the left one. Discussion: The new therapeutic strategies against metastatic cutaneous melanoma condition the appearance of alterations of the pigmentary epithelium of the retina with serous detachments, leading to close monitoring with macular optical coherence tomography.