TY - JOUR AU - Gallego Mora Esperanza, E. AU - Macia, M.L. AU - Chahin, J. AU - Mendez, M.L. AU - Garcia Nieto, V.M. AU - Garcia Perez, J.J. T1 - KT/V Y PCR: MORBILIDAD A LARGO PLAZO SEGUN EL TIPO DE MEMBRANA UTILIZADA TI - KT/V and PCR: Long-term morbidity and type of membrane LA - spa PY - 1994 SP - 126 EP - 130 T2 - Nefrologia SN - 0211-6995 VL - 14 IS - SUPPL. 2 AB - In the present study we have analyzed the influence of the urea kinetic model as an index for dialysis prescription in our hemodialysis patients. We studied 149 patients (98 males, 51 females) during a 5 year period (1988-1992). We calculated volume of urea distribution in relation to sex and body surface. Biochemical, hematological, KT/V, PCR and TAC were determined monthly. Hemodialysis parameters were adjusted in order to obtain: KT/V > 1 and PCR 0.8-1,2 g/kg/day. Mortality and morbidity were also analyzed. Volume of urea distribution showed standard values in 50% of the patients. In the period of study hemodialysis parameters changed significantly. The number of patients with membrane surface > 1,5 m2 inereased 60%, blood flow also increased and dialysis time decreased (p < 0,001). During the first year there was a significant increase of KT/V and PCR. This last parameter was higher (p < 0,01) in the group of patients dialyzed with AN 69 membranes from the beginning (25%) and in those who changed from-cuprophan to AN 69 (20%). In these two groups morbidity also decreased (p < 0,01). Patients dialyzed with bicarbonate bath showed higher PCR values than acetate group (p = NS). There were no significant differences when ESRD etiologies were analyzed. Percentual annual mortality did not change and diabetics together with elderly patients (more than 70 years) showed the worst evolution. We conclude that the application of urea kinetic modeling in our patients as a dialysis prescription guide improve their outcome and morbidity. UR - https://portalciencia.ull.es/documentos/608b26c8289c4a02b5025dd2 DP - Dialnet - Portal de la Investigación ER -