QUIBIONAT
Química y Bioactividad de Compuestos basados en Productos Naturales
Publications (19) Publications in which a researcher has participated
2023
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Phenolic and quinone methide nor-triterpenes as selective NLRP3 inflammasome inhibitors
Bioorganic Chemistry, Vol. 132
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Synthesis and biological evaluation of anthracene-9,10 dione derivatives as CK2 inhibitors
Results in Chemistry, Vol. 6
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Synthesis of Structurally Related Coumarin Derivatives as Antiproliferative Agents
ACS Omega, Vol. 8, Núm. 29, pp. 26479-26496
2022
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Dehydroisohispanolone as a Promising NLRP3 Inhibitor Agent: Bioevaluation and Molecular Docking
Pharmaceuticals, Vol. 15, Núm. 7
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Structure-activity relationships reveal a 2-furoyloxychalcone as a potent cytotoxic and apoptosis inducer for human U-937 and HL-60 leukaemia cells
Bioorganic Chemistry, Vol. 127
2020
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Dehydrohispanolone Derivatives Attenuate the Inflammatory Response through the Modulation of Inflammasome Activation
Journal of Natural Products, Vol. 83, Núm. 7, pp. 2155-2164
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Development of an in vitro screening assay for PIP5K1α lipid kinase and identification of potent inhibitors
FEBS Journal, Vol. 287, Núm. 14, pp. 3042-3064
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The synthetic flavanone 6-methoxy-2-(naphthalen-1-yl)chroman-4-one induces apoptosis and activation of the MAPK pathway in human U-937 leukaemia cells
Bioorganic Chemistry, Vol. 94
2019
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Metal complexes of natural product like-compounds with antitumor activity
Anti-Cancer Agents in Medicinal Chemistry, Vol. 19, Núm. 1, pp. 48-65
2017
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3′-Hydroxy-3,4′-dimethoxyflavone blocks tubulin polymerization and is a potent apoptotic inducer in human SK-MEL-1 melanoma cells
Bioorganic and Medicinal Chemistry, Vol. 25, Núm. 21, pp. 6060-6070
2015
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A new iridoid, verbascoside and derivatives with inhibitory activity against Taq DNA polymerase
Bioorganic and Medicinal Chemistry Letters, Vol. 25, Núm. 4, pp. 914-918
2014
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β-Agarofurans and sesquiterpene pyridine alkaloids from Maytenus spinosa
Journal of Natural Products, Vol. 77, Núm. 8, pp. 1853-1863
2012
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Inhibition of Taq DNA polymerase by iridoid aglycone derivates.
Cellular and molecular biology (Noisy-le-Grand, France), Vol. 58 Suppl
2010
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Cytotoxic triterpenoids from Maytenus retusa
Journal of Natural Products, Vol. 73, Núm. 12, pp. 2029-2034
2009
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Triterpenoids and a lignan from the aerial parts of Maytenus apurimacensis
Journal of Natural Products, Vol. 72, Núm. 6, pp. 1045-1048
2008
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Bis-pyranobenzoquinones as a new family of reversal agents of the multidrug resistance phenotype mediated by P-glycoprotein in mammalian cells and the protozoan parasite Leishmania
Journal of Medicinal Chemistry, Vol. 51, Núm. 22, pp. 7132-7143
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Insect growth regulatory effects of linear diterpenoids and derivatives from Baccharis thymifolia
Journal of Natural Products, Vol. 71, Núm. 2, pp. 190-194
2007
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Terpenoids from the medicinal plant Maytenus ilicifolia
Journal of Natural Products, Vol. 70, Núm. 6, pp. 1049-1052
2004
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Recent studies on natural products as anticancer agents
Current Topics in Medicinal Chemistry, Vol. 4, Núm. 2, pp. 241-265