Publicaciones en colaboración con investigadores/as de Instituto Canario de Investigación del Cáncer (21)

2012

  1. Antiproliferative activity of withanolide derivatives from Jaborosa cabrerae and Jaborosa reflexa. Chemotaxonomic considerations

    Phytochemistry, Vol. 76, pp. 150-157

2010

  1. Antiproliferative activity of novel benzo[b][1,6]naphthyridines in human solid tumor cell lines

    Bioorganic and Medicinal Chemistry Letters, Vol. 20, Núm. 5, pp. 1504-1506

  2. Antiproliferative activity of synthetic naphthoquinones related to lapachol. First synthesis of 5-hydroxylapachol

    Bioorganic and Medicinal Chemistry, Vol. 18, Núm. 7, pp. 2621-2630

  3. Enhancement of antiproliferative activity by molecular simplification of catalpol

    Bioorganic and Medicinal Chemistry, Vol. 18, Núm. 7, pp. 2515-2523

  4. Mitotic arrest induced by a novel family of DNA topoisomerase II inhibitors

    Journal of Medicinal Chemistry, Vol. 53, Núm. 9, pp. 3835-3839

2009

  1. Synthesis and antiproliferative activity of 2,4-disubstituted 6-aryl-7H-pyrrolo[3,2-d]pyrimidin-7-one 5-oxides

    Bioorganic and Medicinal Chemistry, Vol. 17, Núm. 14, pp. 4955-4960

  2. Tessaric acid derivatives induce G2/M cell cycle arrest in human solid tumor cell lines

    Bioorganic and Medicinal Chemistry, Vol. 17, Núm. 17, pp. 6251-6256

2008

  1. β′-Hydroxy-α,β-unsaturated ketones: A new pharmacophore for the design of anticancer drugs. Part 2

    ChemMedChem, Vol. 3, Núm. 11, pp. 1740-1747

  2. γ-Lactones α,β- and β,γ-fused to carbocycles as novel antiproliferative drugs

    Bioorganic and Medicinal Chemistry Letters, Vol. 18, Núm. 19, pp. 5171-5173

2007

  1. Antiproliferative activity of 2-alkyl-4-halopiperidines and 2-alkyl-4-halo-1,2,5,6-tetrahydropyridines in solid tumor cell lines

    Bioorganic and Medicinal Chemistry Letters, Vol. 17, Núm. 10, pp. 2681-2684

  2. Antiproliferative activity of 4-chloro-5,6-dihydro-2H-pyrans. Part 2: Enhancement of drug cytotoxicity

    Bioorganic and Medicinal Chemistry Letters, Vol. 17, Núm. 11, pp. 3087-3090

  3. Cytotoxic effects of C-glycosides in HOS and HeLa cell lines

    Bioorganic and Medicinal Chemistry Letters, Vol. 17, Núm. 13, pp. 3676-3681

  4. Inhibition of DNA topoisomerase I and growth inhibition of human cancer cell lines by an oleanane from Junellia aspera (Verbenaceae)

    Cellular and Molecular Biology, Vol. 53, Núm. 3, pp. 13-17

  5. Novel antiproliferative analogs of the Taq DNA polymerase inhibitor catalpol

    Bioorganic and Medicinal Chemistry Letters, Vol. 17, Núm. 5, pp. 1332-1335

  6. Samarium(II) promoted stereoselective synthesis of antiproliferative cis-β-alkoxy-γ-alkyl-γ-lactones

    Bioorganic and Medicinal Chemistry Letters, Vol. 17, Núm. 1, pp. 18-21

  7. Synthesis and antiproliferative activity of (2R,3R)-disubstituted tetrahydropyrans. Part 2: Effect of side chain homologation

    Bioorganic and Medicinal Chemistry Letters, Vol. 17, Núm. 3, pp. 780-783

2006

  1. Abietane diterpenoids from Salvia pachyphylla and S. clevelandii with cytotoxic activity against human cancer cell lines

    Journal of Natural Products, Vol. 69, Núm. 12, pp. 1803-1805

  2. Synthesis and antiproliferative activity of (2R,3R)-disubstituted tetrahydropyrans

    Bioorganic and Medicinal Chemistry Letters, Vol. 16, Núm. 23, pp. 6135-6138

  3. Synthesis and antiproliferative activity of novel sugiol β-amino alcohol analogs

    European Journal of Medicinal Chemistry, Vol. 41, Núm. 11, pp. 1327-1332

2005

  1. Antiproliferative activity in HL60 cells by tetrasubstituted pyrroles: A structure-activity relationship study

    Bioorganic and Medicinal Chemistry Letters, Vol. 15, Núm. 10, pp. 2487-2490