Publicaciones en colaboración con investigadores/as de Instituto Canario de Investigación del Cáncer (30)

2017

  1. CM363, a novel naphthoquinone derivative which acts as multikinase modulator and overcomes imatinib resistance in chronic myelogenous leukemia

    Oncotarget, Vol. 8, Núm. 18, pp. 29679-29698

2014

  1. A new family of choline kinase inhibitors with antiproliferative and antitumor activity derived from natural products

    Clinical and Translational Oncology, Vol. 17, Núm. 1, pp. 74-84

  2. Yeast cytotoxic sensitivity to the antitumour agent β-lapachone depends mainly on oxidative stress and is largely independent of microtubule- or topoisomerase-mediated DNA damage

    Biochemical Pharmacology, Vol. 92, Núm. 2, pp. 206-219

2013

  1. Achyrofuran is an antibacterial agent capable of killing methicillin-resistant vancomycin-intermediate Staphylococcus aureus in the nanomolar range

    Phytomedicine, Vol. 20, Núm. 2, pp. 133-138

  2. Multicomponent synthesis of antibacterial dihydropyridin and dihydropyran embelin derivatives

    Journal of Organic Chemistry, Vol. 78, Núm. 16, pp. 7977-7985

  3. Preparation and antimalarial activity of semisynthetic lycorenine derivatives

    European Journal of Medicinal Chemistry, Vol. 63, pp. 722-730

  4. Synthesis and cytotoxic activity of metallic complexes of lawsone

    Bioorganic and Medicinal Chemistry, Vol. 21, Núm. 9, pp. 2471-2477

  5. Synthesis and study of antiproliferative, antitopoisomerase II, DNA-intercalating and DNA-damaging activities of arylnaphthalimides

    Bioorganic and Medicinal Chemistry, Vol. 21, Núm. 21, pp. 6484-6495

2012

  1. Antiproliferative activity of withanolide derivatives from Jaborosa cabrerae and Jaborosa reflexa. Chemotaxonomic considerations

    Phytochemistry, Vol. 76, pp. 150-157

  2. Labdanolic acid methyl ester (LAME) exerts anti-inflammatory effects through inhibition of TAK-1 activation

    Toxicology and Applied Pharmacology, Vol. 258, Núm. 1, pp. 109-117

  3. Synthesis and anti-HIV activity of lupane and olean-18-ene derivatives. Absolute configuration of 19,20-epoxylupanes by VCD

    Journal of Natural Products, Vol. 75, Núm. 4, pp. 669-676

  4. Synthesis and antimalarial activity of new haemanthamine-type derivatives

    Bioorganic and Medicinal Chemistry, Vol. 20, Núm. 18, pp. 5464-5472

  5. Unexpected domino synthesis of complex angular naphthoimidazoles

    European Journal of Organic Chemistry, pp. 5757-5766

2011

  1. Benzodihydrofurans from Cyperus teneriffae

    Journal of Natural Products, Vol. 74, Núm. 5, pp. 1061-1065

  2. Dihydro-β-agarofuran sesquiterpenoids from Plenckia integerrima

    Planta Medica, Vol. 77, Núm. 15, pp. 1718-1724

  3. Electronic and cytotoxic properties of 2-amino-naphtho[2,3-b]furan- 4,9-diones

    Journal of Organic Chemistry, Vol. 76, Núm. 6, pp. 1634-1643

  4. Light effect on the stability of β-lapachone in solution: Pathways and kinetics of degradation

    Journal of Pharmacy and Pharmacology, Vol. 63, Núm. 9, pp. 1156-1160

  5. Synthesis and anti-inflammatory activity of ent-kaurene derivatives

    European Journal of Medicinal Chemistry, Vol. 46, Núm. 4, pp. 1291-1305

2010

  1. Acanthamoeba castellanii Neff: In vitro activity against the trophozoite stage of a natural sesquiterpene and a synthetic cobalt(II)-lapachol complex

    Experimental Parasitology, Vol. 126, Núm. 1, pp. 106-108

  2. Synthesis and antiplasmodial activity of lycorine derivatives

    Bioorganic and Medicinal Chemistry, Vol. 18, Núm. 13, pp. 4694-4701