Depressive symptoms in Friedreich ataxia

  1. Antonieta Nieto 1
  2. Atteneri Hernández-Torres 1
  3. Javier Pérez-Flores 1
  4. Fernando Montón 1
  1. 1 Universidad de La Laguna
    info

    Universidad de La Laguna

    San Cristobal de La Laguna, España

    ROR https://ror.org/01r9z8p25

Revista:
International journal of clinical and health psychology

ISSN: 1697-2600

Any de publicació: 2018

Volum: 18

Número: 1

Pàgines: 18-26

Tipus: Article

DOI: 10.1016/J.IJCHP.2017.11.004 DIALNET GOOGLE SCHOLAR

Altres publicacions en: International journal of clinical and health psychology

Resum

Background/Objective: Almost no attention has been paid to depression in Friedreich ataxia (FRDA), a highly disabling cerebellar degenerative disease. Our aim was to study the presence and the profile of depressive symptoms in FRDA and their relationship with demographic-disease variables and cognitive processing speed. Method: The study groups consisted of 57 patients with a diagnosis of FRDA. The Beck Depression Inventory-II was used to assess symptoms of depression. Speed of information processing was measured with a Choice Reaction time task. Results: The mean BDI score for patients was significantly higher than the mean score in the general population. Twenty one percent of participants scored in the moderate/severe range. A Cognitive-Affective score and a Somatic-Motivational score was calculated for each patient. Patients’ scores in both dimensions were significantly higher than the scores in the general population. Demographic and disease variables were not related with symptoms of depression, except for severity of ataxia. Depressive symptoms predict cognitive reaction times. The greater proportion of variance was explained by the Cognitive-Affective dimension. Conclusions: Our data show that both somatic-motivational and cognitive affective symptoms of depression are frequent in individuals with FRDA. In addition, depressive symptoms may influence cognition, especially, the cognitive and affective symptoms.

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Informació de finançament

This work was supported by the Ministerio de Economia y Competitividad (Spain) [grant number PSI 2015-67514-P].

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