Cocaine exposure during pregnancy and postpartum maternal behavior in mice
- María del Pilar Santacruz
- Rosario Josefa Marrero Quevedo
- Juan Manuel Bethencourt Pérez
- Miguel Angel Castellano Gil
- Wenceslao Peñate Castro
ISSN: 1909-9711, 0123-9155
Año de publicación: 2017
Volumen: 20
Número: 1
Páginas: 166-176
Tipo: Artículo
Otras publicaciones en: Acta Colombiana de Psicología
Resumen
O abuso materno de cocaína durante a gestação está relacionado com negligência, maltrato, perturbação do vínculo mãe-filho, o que incide diretamente no desenvolvimento das crianças. Por isso, as diversas problemáticas neurocomportamentais dos filhos de pais drogodependentes poderiam ser atribuídas ao inadequado comportamento materno ou à exposição prénatal à droga. O objetivo desta pesquisa foi analisar os efeitos da administração crônica de cocaína durante a gestação no comportamento materno pós-parto de ratos. Para isso, designaram-se aleatoriamente 21 ratos CD1 fêmeas gestantes para a administração de solução salina e cocaína (25 mg/kg/dia e 50 mg/kg/dia), desde o oitavo até o 21° dia de gestação. Após o parto, durante 20 dias (15 minutos diários), registrou-se individualmente a frequência de apresentação de 16 índices de comportamento materno mediante um etograma. Constatou-se que a cocaína afetou levemente a frequência do comportamento materno, embora possivelmente afete outros parâmetros como latência, duração e sequência desse comportamento.
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