Cocaine exposure during pregnancy and postpartum maternal behavior in mice

  1. María del Pilar Santacruz
  2. Rosario Josefa Marrero Quevedo
  3. Juan Manuel Bethencourt Pérez
  4. Miguel Angel Castellano Gil
  5. Wenceslao Peñate Castro
Revista:
Acta Colombiana de Psicología

ISSN: 1909-9711 0123-9155

Año de publicación: 2017

Volumen: 20

Número: 1

Páginas: 166-176

Tipo: Artículo

DOI: 10.14718/ACP.2017.20.1.8 DIALNET GOOGLE SCHOLAR lock_openAcceso abierto editor

Otras publicaciones en: Acta Colombiana de Psicología

Objetivos de desarrollo sostenible

Resumen

O abuso materno de cocaína durante a gestação está relacionado com negligência, maltrato, perturbação do vínculo mãe-filho, o que incide diretamente no desenvolvimento das crianças. Por isso, as diversas problemáticas neurocomportamentais dos filhos de pais drogodependentes poderiam ser atribuídas ao inadequado comportamento materno ou à exposição prénatal à droga. O objetivo desta pesquisa foi analisar os efeitos da administração crônica de cocaína durante a gestação no comportamento materno pós-parto de ratos. Para isso, designaram-se aleatoriamente 21 ratos CD1 fêmeas gestantes para a administração de solução salina e cocaína (25 mg/kg/dia e 50 mg/kg/dia), desde o oitavo até o 21° dia de gestação. Após o parto, durante 20 dias (15 minutos diários), registrou-se individualmente a frequência de apresentação de 16 índices de comportamento materno mediante um etograma. Constatou-se que a cocaína afetou levemente a frequência do comportamento materno, embora possivelmente afete outros parâmetros como latência, duração e sequência desse comportamento.

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