Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

  1. Paternoster, L. 11
  2. Standl, M. 2
  3. Waage, J. 3
  4. Baurecht, H. 4
  5. Hotze, M. 4
  6. Strachan, D.P. 5
  7. Curtin, J.A. 6
  8. Bønnelykke, K. 3
  9. Tian, C. 7
  10. Takahashi, A. 8
  11. Esparza-Gordillo, J. 910
  12. Alves, A.C. 11
  13. Thyssen, J.P. 3
  14. Den Dekker, H.T. 121212
  15. Ferreira, M.A. 13
  16. Altmaier, E. 222
  17. Sleiman, P.M.A. 1415
  18. Xiao, F.L. 16
  19. Gonzalez, J.R. 171819
  20. Marenholz, I. 910
  21. Kalb, B. 910
  22. Pino-Yanes, M. 202122
  23. Xu, C.-J. 2323
  24. Carstensen, L. 24
  25. Groen-Blokhuis, M.M. 25
  26. Venturini, C. 26
  27. Pennell, C.E. 27
  28. Barton, S.J. 28
  29. Levin, A.M. 29
  30. Curjuric, I. 3031
  31. Bustamante, M. 17181932
  32. Kreiner-Møller, E. 3
  33. Lockett, G.A. 33
  34. Bacelis, J. 34
  35. Bunyavanich, S. 35
  36. Myers, R.A. 36
  37. Matanovic, A. 910
  38. Kumar, A. 30313738
  39. Tung, J.Y. 7
  40. Hirota, T. 39
  41. Kubo, M. 40
  42. McArdle, W.L. 1
  43. Henderson, A.J. 1
  44. Kemp, J.P. 1141
  45. Zheng, J. 11
  46. Smith, G.D. 11
  47. Rüschendorf, F. 9
  48. Bauerfeind, A. 9
  49. Lee-Kirsch, M.A. 42
  50. Arnold, A. 43
  51. Homuth, G. 44
  52. Schmidt, C.O. 45
  53. Mangold, E. 46
  54. Cichon, S. 4647484950
  55. Keil, T. 1051
  56. Rodríguez, E. 4
  57. Peters, A. 252
  58. Franke, A. 53
  59. Lieb, W. 53
  60. Novak, N. 54
  61. Fölster-Holst, R. 4
  62. Horikoshi, M. 38
  63. Pekkanen, J. 5556
  64. Sebert, S. 5757
  65. Husemoen, L.L. 58
  66. Grarup, N. 59
  67. De Jongste, J.C. 12
  68. Rivadeneira, F. 121212
  69. Hofman, A. 12
  70. Jaddoe, V.W.V. 121212
  71. Pasmans, S.G.M.A. 12
  72. Elbert, N.J. 1212
  73. Uitterlinden, A.G. 1212
  74. Marks, G.B. 60
  75. Thompson, P.J. 6162
  76. Matheson, M.C. 63
  77. Robertson, C.F. 64
  78. Ried, J.S. 2
  79. Li, J. 14
  80. Zuo, X.B. 16
  81. Zheng, X.D. 16
  82. Yin, X.Y. 16
  83. Sun, L.D. 16
  84. McAleer, M.A. 6566
  85. O'Regan, G.M. 66
  86. Fahy, C.M.R. 67
  87. Campbell, L.E. 68
  88. Macek, M. 69
  89. Kurek, M. 70
  90. Hu, D. 20
  91. Eng, C. 20
  92. Postma, D.S. 23
  93. Feenstra, B. 24
  94. Geller, F. 24
  95. Hottenga, J.J. 25
  96. Middeldorp, C.M. 25
  97. Hysi, P. 26
  98. Bataille, V. 26
  99. Spector, T. 26
  100. Tiesler, C.M.T. 271
  101. Thiering, E. 271
  102. Pahukasahasram, B. 72
  103. Yang, J.J. 73
  104. Imboden, M. 3031
  105. Huntsman, S. 20
  106. Vilor-Tejedor, N. 171819
  107. Relton, C.L. 174
  108. Myhre, R. 75
  109. Nystad, W. 75
  110. Custovic, A. 6
  111. Weiss, S.T. 76
  112. Meyers, D.A. 77
  113. Söderhäll, C. 3737
  114. Melén, E. 3778
  115. Ober, C. 36
  116. Raby, B.A. 76
  117. Simpson, A. 6
  118. Jacobsson, B. 3475
  119. Holloway, J.W. 3379
  120. Bisgaard, H. 3
  121. Sunyer, J. 17181980
  122. Probst-Hensch, N.M. 3031
  123. Williams, L.K. 7281
  124. Godfrey, K.M. 2882
  125. Wang, C.A. 27
  126. Boomsma, D.I. 2525
  127. Melbye, M. 248384
  128. Koppelman, G.H. 85
  129. Jarvis, D. 8687
  130. McLean, W.H.I. 68
  131. Irvine, A.D. 656667
  132. Zhang, X.J. 16
  133. Hakonarson, H. 1415
  134. Gieger, C. 222
  135. Burchard, E.G. 2020
  136. Martin, N.G. 13
  137. Duijts, L. 121212
  138. Linneberg, A. 588388
  139. Jarvelin, M.-R. 57578789
  140. Nöthen, M.M. 4647
  141. Lau, S. 10
  142. Hübner, N. 9
  143. Lee, Y.-A. 910
  144. Tamari, M. 39
  145. Hinds, D.A. 7
  146. Glass, D. 26
  147. Brown, S.J. 6890
  148. Heinrich, J. 2
  149. Evans, D.M. 1141
  150. Weidinger, S. 4
  151. Show all authors +
  1. 1 University of Bristol
    info

    University of Bristol

    Brístol, Reino Unido

    GRID grid.5337.2

  2. 2 Helmholtz Zentrum München
    info

    Helmholtz Zentrum München

    Múnich, Alemania

    GRID grid.4567.0

  3. 3 University of Copenhagen
    info

    University of Copenhagen

    Copenhague, Dinamarca

    GRID grid.5254.6

  4. 4 Department of Dermatology, Allergology and Venereology, University Hospital Schleswig-Holstein, Campus Kiel
  5. 5 University of London
    info

    University of London

    Londres, Reino Unido

    GRID grid.4464.2

  6. 6 University of Manchester
    info

    University of Manchester

    Mánchester, Reino Unido

    GRID grid.5379.8

  7. 7 23andMe, Inc.
  8. 8 Laboratory for Statistical Analysis, Center for Integrative Medical Sciences, Institute of Physical and Chemical Research (RIKEN)
  9. 9 Max Delbrück Center (MDC) for Molecular Medicine
  10. 10 Charité
    info

    Charité

    Berlín, Alemania

    GRID grid.6363.0

  11. 11 Imperial College London
    info

    Imperial College London

    Londres, Reino Unido

    GRID grid.7445.2

  12. 12 Erasmus University Medical Center
    info

    Erasmus University Medical Center

    Róterdam, Holanda

    GRID grid.5645.2

  13. 13 QIMR Berghofer Medical Research Institute
    info

    QIMR Berghofer Medical Research Institute

    Brisbane, Australia

    GRID grid.1049.c

  14. 14 Children's Hospital of Philadelphia
    info

    Children's Hospital of Philadelphia

    Filadelfia, Estados Unidos

    GRID grid.239552.a

  15. 15 Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania
  16. 16 Institute of Dermatology, Anhui Medical University
  17. 17 Instituto de Salud Global de Barcelona
    info

    Instituto de Salud Global de Barcelona

    Barcelona, España

  18. 18 Universitat Pompeu Fabra
    info

    Universitat Pompeu Fabra

    Barcelona, España

    GRID grid.5612.0

  19. 19 Centro de Investigación Biomédica en Red sobre Epidemiología Y Salud Pública
    info

    Centro de Investigación Biomédica en Red sobre Epidemiología Y Salud Pública

    Madrid, España

    GRID grid.466571.7

  20. 20 University of California, San Francisco
    info

    University of California, San Francisco

    San Francisco, Estados Unidos

    GRID grid.266102.1

  21. 21 Centro de Investigacion Biomedica en Red de Enfermedades Respiratorias
    info

    Centro de Investigacion Biomedica en Red de Enfermedades Respiratorias

    Madrid, España

  22. 22 Hospital Universitario Nuestra Señora de Candelaria
    info

    Hospital Universitario Nuestra Señora de Candelaria

    Santa Cruz de Tenerife, España

    GRID grid.411331.5

  23. 23 University of Groningen
    info

    University of Groningen

    Groninga, Holanda

    GRID grid.4830.f

  24. 24 Department of Epidemiology Research, Statens Serum Institut
  25. 25 VU University Amsterdam
    info

    VU University Amsterdam

    Ámsterdam, Holanda

    GRID grid.12380.38

  26. 26 King's College London
    info

    King's College London

    Londres, Reino Unido

    GRID grid.13097.3c

  27. 27 School of Women's and Infants' Health, University of Western Australia
  28. 28 Medical Research Council (MRC), Lifecourse Epidemiology Unit, University of Southampton
  29. 29 Department of Public Health Sciences, Henry Ford Health System
  30. 30 Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute
  31. 31 University of Basel
    info

    University of Basel

    Basilea, Suiza

    GRID grid.6612.3

  32. 32 Centro de Regulación Genómica
    info

    Centro de Regulación Genómica

    Barcelona, España

    GRID grid.11478.3b

  33. 33 Human Development and Health, Faculty of Medicine, University of Southampton
  34. 34 Sahlgrenska University Hospital
    info

    Sahlgrenska University Hospital

    Gotemburgo, Suecia

    GRID grid.1649.a

  35. 35 Icahn School of Medicine at Mount Sinai
    info

    Icahn School of Medicine at Mount Sinai

    Nueva York, Estados Unidos

    GRID grid.59734.3c

  36. 36 University of Chicago
    info

    University of Chicago

    Chicago, Estados Unidos

    GRID grid.170205.1

  37. 37 Karolinska Institute
    info

    Karolinska Institute

    Estocolmo, Suecia

    GRID grid.4714.6

  38. 38 Wellcome Trust, Centre for Human Genetics, University of Oxford
  39. 39 Laboratory for Respiratory and Allergic Diseases, Center for Integrative Medical Sciences, Institute of Physical and Chemical Research (RIKEN)
  40. 40 Laboratory for Genotyping Development, Center for Integrative Medical Sciences, Institute of Physical and Chemical Research (RIKEN)
  41. 41 University of Queensland
    info

    University of Queensland

    Brisbane, Australia

    GRID grid.1003.2

  42. 42 Dresden University of Technology
    info

    Dresden University of Technology

    Dresde, Alemania

    GRID grid.4488.0

  43. 43 Clinic and Polyclinic of Dermatology, University Medicine Greifswald
  44. 44 University of Greifswald
    info

    University of Greifswald

    Greifswald, Alemania

    GRID grid.5603.0

  45. 45 Institute for Community Medicine, Study of Health in Pomerania, KEF (Klinisch-Epidemiologische Forschung), University Medicine Greifswald
  46. 46 Institute of Human Genetics, University of Bonn
  47. 47 University of Bonn
    info

    University of Bonn

    Bonn, Alemania

    GRID grid.10388.32

  48. 48 Division of Medical Genetics, University Hospital Basel
  49. 49 Department of Biomedicine, University of Basel
  50. 50 Forschungszentrum Jülich
    info

    Forschungszentrum Jülich

    Jülich, Alemania

    GRID grid.8385.6

  51. 51 University of Würzburg
    info

    University of Würzburg

    Wurzburgo, Alemania

    GRID grid.8379.5

  52. 52 DZHK (German Research Centre for Cardiovascular Research), Munich Heart Alliance
  53. 53 Kiel University
    info

    Kiel University

    Kiel, Alemania

    GRID grid.9764.c

  54. 54 Department of Dermatology and Allergy, University of Bonn Medical Center
  55. 55 Unit of Living Environment and Health, National Institute for Health and Welfare
  56. 56 University of Helsinki
    info

    University of Helsinki

    Helsinki, Finlandia

    GRID grid.7737.4

  57. 57 University of Oulu
    info

    University of Oulu

    Oulu, Finlandia

    GRID grid.10858.34

  58. 58 Research Centre for Prevention and Health, Capital Region of Denmark
  59. 59 Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen
  60. 60 University of Sydney
    info

    University of Sydney

    Sídney, Australia

    GRID grid.1013.3

  61. 61 Lung Institute of Western Australia, Queen Elizabeth II Medical Centre
  62. 62 School of Medicine and Pharmacology, University of Western Australia
  63. 63 Melbourne School of Population and Global Health, University of Melbourne
  64. 64 Murdoch Childrens Research Institute
    info

    Murdoch Childrens Research Institute

    Melbourne, Australia

    GRID grid.1058.c

  65. 65 National Children’s Research Centre
    info

    National Children’s Research Centre

    Crumlin, Irlanda

    GRID grid.452722.4

  66. 66 Department of Pediatric Dermatology, Our Lady's Children's Hospital
  67. 67 Trinity College Dublin
    info

    Trinity College Dublin

    Dublín, Irlanda

    GRID grid.8217.c

  68. 68 University of Dundee
    info

    University of Dundee

    Dundee, Reino Unido

    GRID grid.8241.f

  69. 69 Department of Biology and Medical Genetics, University Hospital Motol, 2nd Faculty of Medicine, Charles University
  70. 70 Department of Clinical Allergology, Pomeranian Medical University
  71. 71 Klinikum der Universität München
    info

    Klinikum der Universität München

    Múnich, Alemania

    GRID grid.411095.8

  72. 72 Center for Health Policy and Health Services Research, Henry Ford Health System
  73. 73 University of Michigan–Ann Arbor
    info

    University of Michigan–Ann Arbor

    Ann Arbor, Estados Unidos

    GRID grid.214458.e

  74. 74 Institute of Genetic Medicine, Newcastle University
  75. 75 Division of Epidemiology, Norwegian Institute of Public Health
  76. 76 Harvard Medical School
    info

    Harvard Medical School

    Boston, Estados Unidos

    GRID grid.471403.5

  77. 77 Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine
  78. 78 Sachs' Children's Hospital
  79. 79 Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton
  80. 80 Hospital del Mar
    info

    Hospital del Mar

    Barcelona, España

    GRID grid.411142.3

  81. 81 Department of Internal Medicine, Henry Ford Health System
  82. 82 University of Southampton
    info

    University of Southampton

    Southampton, Reino Unido

    GRID grid.5491.9

  83. 83 Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen
  84. 84 Stanford University School of Medicine
    info

    Stanford University School of Medicine

    Stanford, Estados Unidos

    GRID grid.471392.a

  85. 85 University of Groningen, University Medical Center Groningen, Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, Groningen Research Institute for Asthma and COPD (GRIAC)
  86. 86 Respiratory Epidemiology, Occupational Medicine and Public Health, National Heart and Lung Institute, Imperial College London
  87. 87 Public Health England
    info

    Public Health England

    Londres, Reino Unido

  88. 88 Copenhagen University Hospital
    info

    Copenhagen University Hospital

    Copenhague, Dinamarca

    GRID grid.4973.9

  89. 89 Unit of Primary Care, Oulu University Hospital
  90. 90 Department of Dermatology, Ninewells Hospital and Medical School
Journal:
Nature Genetics

ISSN: 1546-1718

Year of publication: 2015

Volume: 47

Issue: 12

Pages: 1449-1456

Type: Article

Export: RIS
DOI: 10.1038/ng.3424 PMID: 26482879 SCOPUS: 2-s2.0-84949087646 GOOGLE SCHOLAR
Data source: Scopus