HIV-1 protease inhibitors from inverse design in the substrate envelope exhibit subnanomolar binding to drug-resistant variants

  1. Altman, M.D.
  2. Ali, A.
  3. Reddy, G.S.K.K.
  4. Nalam, M.N.L.
  5. Anjum, S.G.
  6. Cao, H.
  7. Chellappan, S.
  8. Kairys, V.
  9. Fernandes, M.X.
  10. Gilson, M.K.
  11. Schiffer, C.A.
  12. Rana, T.M.
  13. Tidor, B.
Journal:
Journal of the American Chemical Society

ISSN: 0002-7863

Year of publication: 2008

Volume: 130

Issue: 19

Pages: 6099-6113

Type: Article

DOI: 10.1021/JA076558P GOOGLE SCHOLAR