X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19

  1. Asano, T. 1
  2. Boisson, B. 123
  3. Onodi, F. 4
  4. Matuozzo, D. 23
  5. Moncada-Velez, M. 1
  6. Maglorius Renkilaraj, M.R.L. 23
  7. Zhang, P. 1
  8. Meertens, L. 4
  9. Bolze, A. 5
  10. Materna, M. 23
  11. Korniotis, S. 6
  12. Gervais, A. 23
  13. Talouarn, E. 23
  14. Bigio, B. 1
  15. Seeleuthner, Y. 23
  16. Bilguvar, K. 7
  17. Zhang, Y. 88
  18. Neehus, A.-L. 23
  19. Ogishi, M. 1
  20. Pelham, S.J. 1
  21. Le Voyer, T. 23
  22. Rosain, J. 23
  23. Philippot, Q. 23
  24. Soler-Palacín, P. 91011
  25. Colobran, R. 101112
  26. Martin-Nalda, A. 91011
  27. Rivière, J.G. 91011
  28. Tandjaoui-Lambiotte, Y. 13
  29. Chaïbi, K. 1415
  30. Shahrooei, M. 1617
  31. Darazam, I.A. 1819
  32. Olyaei, N.A. 1617
  33. Mansouri, D. 202122
  34. Hatipoğlu, N. 23
  35. Palabiyik, F. 23
  36. Ozcelik, T. 24
  37. Novelli, G. 25
  38. Novelli, A. 26
  39. Casari, G. 2728
  40. Aiuti, A. 2729
  41. Carrera, P. 28
  42. Bondesan, S. 28
  43. Barzaghi, F. 29
  44. Rovere-Querini, P. 2730
  45. Tresoldi, C. 31
  46. Franco, J.L. 32
  47. Rojas, J. 32
  48. Reyes, L.F. 33
  49. Bustos, I.G. 33
  50. Arias, A.A. 13232
  51. Morelle, G. 34
  52. Christèle, K. 34
  53. Troya, J. 35
  54. Planas-Serra, L. 3637
  55. Schlüter, A. 3637
  56. Gut, M. 38
  57. Pujol, A. 363739
  58. Allende, L.M. 4041
  59. Rodriguez-Gallego, C. 4243
  60. Flores, C. 44454647
  61. Cabrera-Marante, O. 40
  62. Pleguezuelo, D.E. 40
  63. de Diego, R.P. 48
  64. Keles, S. 49
  65. Aytekin, G. 50
  66. Akcan, O.M. 49
  67. Bryceson, Y.T. 51
  68. Bergman, P. 5152
  69. Brodin, P. 51
  70. Smole, D. 53
  71. Smith, C.I.E. 5152
  72. Norlin, A.-C. 52
  73. Campbell, T.M. 51
  74. Covill, L.E. 51
  75. Hammarström, L. 51
  76. Pan-Hammarström, Q. 51
  77. Abolhassani, H. 5154
  78. Mane, S. 7
  79. Marr, N. 55
  80. Ata, M. 55
  81. Al Ali, F. 55
  82. Khan, T. 55
  83. Spaan, A.N. 156
  84. Dalgard, C.L. 5758
  85. Bonfanti, P. 59
  86. Biondi, A. 60
  87. Tubiana, S. 6162
  88. Burdet, C. 6163
  89. Nussbaum, R. 64
  90. Kahn-Kirby, A. 64
  91. Snow, A.L. 65
  92. Bustamante, J. 1223
  93. Puel, A. 123
  94. Boisson-Dupuis, S. 123
  95. Zhang, S.-Y. 123
  96. Béziat, V. 123
  97. Lifton, R.P. 17
  98. Bastard, P. 23
  99. Notarangelo, L.D. 88
  100. Abel, L. 123
  101. Su, H.C. 8866
  102. Jouanguy, E. 123
  103. Amara, A. 4
  104. Soumelis, V. 667
  105. Cobat, A. 123
  106. Zhang, Q. 1
  107. Casanova, J.-L. 12368
  108. Show all authors +
  1. 1 Rockefeller University
    info

    Rockefeller University

    Nueva York, Estados Unidos

    ROR https://ror.org/0420db125

  2. 2 Necker-Enfants Malades Hospital
    info

    Necker-Enfants Malades Hospital

    París, Francia

    ROR https://ror.org/05tr67282

  3. 3 University of Paris, Imagine Institute
  4. 4 Laboratory of Genomes & Cell Biology of Disease, INSERM U944, CNRS UMR7212, University of Paris, Research Institute of Saint-Louis, Saint-Louis Hospital
  5. 5 Helix, San Mateo, CA, USA
  6. 6 University of Paris
  7. 7 Yale School of Medicine
    info

    Yale School of Medicine

    New Haven, Estados Unidos

  8. 8 National Institute of Allergy and Infectious Diseases
    info

    National Institute of Allergy and Infectious Diseases

    Bethesda, Estados Unidos

    ROR https://ror.org/043z4tv69

  9. 9 Infection in Immunocompromised Pediatric Patients Research Group, Vall d'Hebron Research Institute (VHIR)
  10. 10 Universitat Autònoma de Barcelona
    info

    Universitat Autònoma de Barcelona

    Barcelona, España

    ROR https://ror.org/052g8jq94

  11. 11 Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies
  12. 12 Vall d'Hebron Institut de Recerca
    info

    Vall d'Hebron Institut de Recerca

    Barcelona, España

    ROR https://ror.org/01d5vx451

  13. 13 AP-HP, Avicenne Hospital, Intensive Care Unit
  14. 14 Anesthesiology and Critical Care Medicine Department, APHP, Avicenne Hospital
  15. 15 Pierre and Marie Curie University
    info

    Pierre and Marie Curie University

    París, Francia

  16. 16 Specialized Immunology Laboratory of Dr. Shahrooei, Sina Medical Complex
  17. 17 KU Leuven
    info

    KU Leuven

    Lovaina, Bélgica

    ROR https://ror.org/05f950310

  18. 18 Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences
  19. 19 Department of Infectious Diseases and Tropical Medicine, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences
  20. 20 Department of Clinical Immunology and Infectious Diseases, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences
  21. 21 Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Masih Daneshvari Hospital, Shahid Beheshti, University of Medical Sciences
  22. 22 Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti
  23. 23 Pediatric Infectious Diseases Unit, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences
  24. 24 Department of Molecular Biology and Genetics, University of Bilkent
  25. 25 University of Rome Tor Vergata
    info

    University of Rome Tor Vergata

    Roma, Italia

    ROR https://ror.org/02p77k626

  26. 26 Laboratory of Medical Genetics, Translational Cytogenomics Research Unit, Bambino Gesù Children Hospital, IRCCS
  27. 27 Vita-Salute San Raffaele University
    info

    Vita-Salute San Raffaele University

    Milán, Italia

    ROR https://ror.org/01gmqr298

  28. 28 Clinical Genomics, IRCCS San Raffaele Scientific Institute
  29. 29 San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) and Pediatric Immunohematology Unit and BMT Program, IRCCS San Raffaele Scientific Institute
  30. 30 Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute
  31. 31 Molecular Hematology Unit, IRCCS Ospedale San Raffaele
  32. 32 Universidad de Antioquia
    info

    Universidad de Antioquia

    Medellín, Colombia

    ROR https://ror.org/03bp5hc83

  33. 33 Universidad de La Sabana
    info

    Universidad de La Sabana

    Chía, Colombia

    ROR https://ror.org/02sqgkj21

  34. 34 University of Paris-Saclay
    info

    University of Paris-Saclay

    Gif-sur-Yvette, Francia

    ROR https://ror.org/03xjwb503

  35. 35 Hospital Infanta Leonor
    info

    Hospital Infanta Leonor

    Madrid, España

    ROR https://ror.org/05nfzf209

  36. 36 Institut d'Investigació Biomédica de Bellvitge
    info

    Institut d'Investigació Biomédica de Bellvitge

    Barcelona, España

    ROR https://ror.org/0008xqs48

  37. 37 Instituto de Salud Carlos III
    info

    Instituto de Salud Carlos III

    Madrid, España

    ROR https://ror.org/00ca2c886

  38. 38 Centro de Regulación Genómica
    info

    Centro de Regulación Genómica

    Barcelona, España

    ROR https://ror.org/03wyzt892

  39. 39 Institució Catalana de Recerca i Estudis Avançats
    info

    Institució Catalana de Recerca i Estudis Avançats

    Barcelona, España

    ROR https://ror.org/0371hy230

  40. 40 Hospital Universitario 12 de Octubre
    info

    Hospital Universitario 12 de Octubre

    Madrid, España

    ROR https://ror.org/00qyh5r35

  41. 41 Universidad Complutense de Madrid
    info

    Universidad Complutense de Madrid

    Madrid, España

    ROR 02p0gd045

  42. 42 Hospital de Gran Canaria Dr. Negrin
    info

    Hospital de Gran Canaria Dr. Negrin

    Las Palmas de Gran Canaria, España

    ROR https://ror.org/00s4vhs88

  43. 43 Department of Clinical Sciences, University of Fernando Pessoa Canarias
  44. 44 Genomics Division, Institute of Technology and Renewable Energies (ITER)
  45. 45 Centro de Investigacion Biomedica en Red de Enfermedades Respiratorias
    info

    Centro de Investigacion Biomedica en Red de Enfermedades Respiratorias

    Madrid, España

  46. 46 Hospital Universitario Nuestra Señora de Candelaria
    info

    Hospital Universitario Nuestra Señora de Candelaria

    Santa Cruz de Tenerife, España

    ROR https://ror.org/005a3p084

  47. 47 Universidad de La Laguna
    info

    Universidad de La Laguna

    San Cristobal de La Laguna, España

    ROR https://ror.org/01r9z8p25

  48. 48 Hospital Universitario La Paz
    info

    Hospital Universitario La Paz

    Madrid, España

    ROR https://ror.org/01s1q0w69

  49. 49 Necmettin Erbakan University, Meram Medical Faculty, Division of Pediatric Allergy and Immunology
  50. 50 Konya City Hospital, Division of Allergy and Immunology
  51. 51 Karolinska Institute
    info

    Karolinska Institute

    Estocolmo, Suecia

    ROR https://ror.org/056d84691

  52. 52 Karolinska University Hospital
    info

    Karolinska University Hospital

    Estocolmo, Suecia

    ROR https://ror.org/00m8d6786

  53. 53 Central Hospital-Anesthesia and Intensive Care Unit
  54. 54 Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences
  55. 55 Department of Immunology, Research Branch, Sidra Medicine
  56. 56 University Medical Center Utrecht
    info

    University Medical Center Utrecht

    Utrecht, Holanda

    ROR https://ror.org/0575yy874

  57. 57 Department of Anatomy, Physiology & Genetics Uniformed Services University of the Health Sciences, MD
  58. 58 American Genome Center, Uniformed Services University of the Health Sciences, MD
  59. 59 Department of Infectious Diseases, San Gerardo Hospital-University of Milano-Bicocca
  60. 60 University of Milano-Bicocca
    info

    University of Milano-Bicocca

    Milán, Italia

    ROR https://ror.org/01ynf4891

  61. 61 Centre d'investigation clinique
    info

    Centre d'investigation clinique

    Nantes, Francia

    ROR https://ror.org/02ct41845

  62. 62 Hôpital Bichat Claude Bernard, APHP
  63. 63 Université de Paris, IAME, INSERM UMR 1137
  64. 64 Invitae, San Francisco, CA, USA
  65. 65 Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, MD
  66. 66 Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, PA
  67. 67 APHP, Hôpital Saint-Louis, Department of Immunology-Histocompatibility
  68. 68 Howard Hughes Medical Institute
    info

    Howard Hughes Medical Institute

    Chevy Chase, Estados Unidos

    ROR https://ror.org/006w34k90

Journal:
Science immunology

ISSN: 2470-9468

Year of publication: 2021

Volume: 6

Issue: 62

Type: Article

DOI: 10.1126/SCIIMMUNOL.ABL4348 PMID: 34413140 SCOPUS: 2-s2.0-85113561257 GOOGLE SCHOLAR lock_openOpen access editor
Data source: Scopus