Cimicifuga racemosa (L.) Nutt. en el tratamiento de los síntomas vasomotores de la menopausiarevisión

  1. Sánchez-Mateo, Candelaria C. 1
  2. García-Bienes, Hilaria M. 1
  1. 1 Universidad de La Laguna
    info

    Universidad de La Laguna

    San Cristobal de La Laguna, España

    ROR https://ror.org/01r9z8p25

Revue:
Ars pharmaceutica

ISSN: 2340-9894,  0004-2927

Année de publication: 2022

Volumen: 63

Número: 2

Pages: 178-188

Type: Article

DOI: 10.30827/ARS.V63I2.21894 DIALNET GOOGLE SCHOLAR lock_openAccès ouvert editor

D'autres publications dans: Ars pharmaceutica

Résumé

Introduction: Several studies have shown that preparations based on the rhizomes and roots of black cohosh (Cimicifuga racemosa (L.) Nutt.) can be useful in alleviating the menopausal symptoms. The aim of this study is to perform an update bibliographic review of the efficacy and safety of black cohosh in the treatment of the vasomotor symptoms of menopause. Method: A review of published articles from January 2005 to March 2021 in the resource search engine of the University of La Laguna, el punto Q”. Randomized and controlled clinical trials, which had the key words in the abstract, text or title, in both English and Spanish, were selected. Results: We found 13 trials which met the selection criteria. The studies reviewed showed that the black cohosh preparations (mainly commercial extracts standardized in their content of active ingredients) produced in most of the studies a significant reduction compared to placebo in the vegetative (hot flashes and night sweats) and psychological symptoms of menopause, as well as an improvement in the quality of life. No serious adverse effects were reported at the dose administered. Conclusions: Cimicifuga racemosa extracts can be effective and safe for the treatment of vegetative and psychological symptoms of menopause, being well tolerated. However, more clinical trials with a larger number of patients, more extensive, the use of standardized preparations, as well as similar criteria for inclusion and assessment of symptoms, are necessary to obtain more conclusive data.

Références bibliographiques

  • Grupo de trabajo de la Guía de Práctica Clínica sobre el abordaje de síntomas vasomotores y vaginales asociados a la menopausia y postmenopausia. Guía de Práctica Clínica sobre el abordaje de síntomas vasomotores y vaginales asociados a la menopausia y postmenopausia. Ministerio de Sanidad, Servicios Sociales e Igualdad. Agencia de Evaluación de Tecnologías Sanitarias de Andalucía (AETSA); 2017. Guía de Práctica Clínica en el SNS.
  • Allué J, Alonso MJ. Fitoterapia ginecológica. En: Castillo García E, Martínez Solís I, editoras. Manual de fitoterapia. 2ª Edición. Barcelona: Elsevier España, S.L.U.; 2016. p. 337-351.
  • Dietz BM, Hajirahimkhan A, Dunlap TL, Bolton JL. Botanicals and their bioactive phytochemicals for women’s health. Pharmacol Rev. 2016; 68: 1026- 1073. http://dx.doi.org/10.1124/pr-115.010843.
  • Guo Y, Wang X, Zhang F, et al. Traditional uses, phytochemistry, pharmacology and toxicology of the genus Cimicifuga: a review. J Ethnopharmacol. 2017; 209: 264-282. doi: 10.1016/j.jep.2017.07.040.
  • Vanaclocha B, Cañigueral S, Fitoterapia, Vademécum de prescripción. 5 ª ed. Barcelona: Elsevier España, S.L.U.; 2019 p. 231- 232.
  • Wuttke W, Seidlová-Wuttke D. Black cohosh (Cimicifuga racemosa) is a non-estrogenic alternative to hormone replacement therapy. Clin Phytoscience. 2015; 1: 12. doi: 10.1186/s40816-015-0013-0.
  • Pkhaladze L, Davidova N, Khomasuridze A, Shengelia R, Panossian A. Actaea racemosa L. is more efective in combination with Rhodiola rosea L. for relief of menopausal symptoms: A randomized, double-blind, placebo-controlled study. Pharmaceuticals. 2020; 21 May; 13 (5): 102. doi: 10.3390 / ph13050102.
  • Mehrpooya M, Rabiee S, Larki-Harchegani A, et al. A comparative study on the effect of black cohosh and evening primrose oil on menopausal hot flashes. J Edu Health Promot. 2018; 7: 36. doi: 10.4103/jehp.jehp_81_17.
  • Tanmahasamut P, Vichinsartvichai P, Rattanachaiyanont M, Techatraisak K, Dangrat C, Sardod P. Cimicifuga racemosa extract for relieving menopausal symptoms: a randomized controlled trial. Climateric. 2015; 18: 79-85. doi: 10.3109/13697137.2014.933410.
  • Mohammad-Alizadeh-Charandabi S, Shahnazi M, Nahaee J, Bayatipayan S. Efficacy of black cohosh (Cimicifuga racemosa L.) in treating early symptoms of menopause: a randomized clinical trial. Chinese Med. 2013; 8:20. doi: 10.1186/1749-8546-8-20.
La source de données: Dialnet