Química y Bioactividad de Compuestos basados en Productos Naturales
QUIBIONAT
Hospital Universitario Nuestra Señora de Candelaria
Santa Cruz de Tenerife, EspañaPublications in collaboration with researchers from Hospital Universitario Nuestra Señora de Candelaria (22)
2023
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Synthesis of Structurally Related Coumarin Derivatives as Antiproliferative Agents
ACS Omega, Vol. 8, Núm. 29, pp. 26479-26496
2018
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Lawsone, Juglone, and β-Lapachone Derivatives with Enhanced Mitochondrial-Based Toxicity
ACS Chemical Biology, Vol. 13, Núm. 8, pp. 1950-1957
2017
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5-Ethynylarylnaphthalimides as antitumor agents: Synthesis and biological evaluation
Bioorganic and Medicinal Chemistry, Vol. 25, Núm. 6, pp. 1976-1983
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Synthesis and antibacterial activity of new symmetric polyoxygenated dibenzofurans
European Journal of Medicinal Chemistry, Vol. 141, pp. 178-187
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Synthesis and biological evaluation of naphthoquinone-coumarin conjugates as topoisomerase II inhibitors
Bioorganic and Medicinal Chemistry Letters, Vol. 27, Núm. 3, pp. 484-489
2016
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Domino Synthesis of Embelin Derivatives with Antibacterial Activity
Journal of Natural Products, Vol. 79, Núm. 4, pp. 970-977
2015
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Structure and antimicrobial activity of phloroglucinol derivatives from achyrocline satureioides
Journal of Natural Products, Vol. 78, Núm. 1, pp. 93-102
2014
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Yeast cytotoxic sensitivity to the antitumour agent β-lapachone depends mainly on oxidative stress and is largely independent of microtubule- or topoisomerase-mediated DNA damage
Biochemical Pharmacology, Vol. 92, Núm. 2, pp. 206-219
2013
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Achyrofuran is an antibacterial agent capable of killing methicillin-resistant vancomycin-intermediate Staphylococcus aureus in the nanomolar range
Phytomedicine, Vol. 20, Núm. 2, pp. 133-138
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Multicomponent synthesis of antibacterial dihydropyridin and dihydropyran embelin derivatives
Journal of Organic Chemistry, Vol. 78, Núm. 16, pp. 7977-7985
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Synthesis and study of antiproliferative, antitopoisomerase II, DNA-intercalating and DNA-damaging activities of arylnaphthalimides
Bioorganic and Medicinal Chemistry, Vol. 21, Núm. 21, pp. 6484-6495
2010
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Evaluation of labdane derivatives as potential anti-inflammatory agents
European Journal of Medicinal Chemistry, Vol. 45, Núm. 7, pp. 3155-3161
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Synthesis and induction of apoptosis signaling pathway of ent-kaurane derivatives
Bioorganic and Medicinal Chemistry, Vol. 18, Núm. 4, pp. 1724-1735
2009
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The lupane-type triterpene 30-oxo-calenduladiol is a CCR5 antagonist with anti-HIV-1 and anti-chemotactic activities
Journal of Biological Chemistry, Vol. 284, Núm. 24, pp. 16609-16620
2008
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An efficient synthesis of embelin derivatives through domino Knoevenagel hetero Diels-Alder reactions under microwave irradiation
Tetrahedron, Vol. 64, Núm. 37, pp. 8938-8942
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Design and synthesis of a novel series of pyranonaphthoquinones as topoisomerase II catalytic inhibitors
Journal of Medicinal Chemistry, Vol. 51, Núm. 21, pp. 6761-6772
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New terpenoids from Maytenus apurimacensis as MDR reversal agents in the parasite Leishmania
Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 3, pp. 1425-1430
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Structure and estrogenic activity of new lignans from Iryanthera lancifolia
Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 6, pp. 3387-3394
2007
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Double domino Knoevenagel hetero Diels-Alder strategy towards bis-pyrano-1,4-benzoquinones
Tetrahedron, Vol. 63, Núm. 14, pp. 3066-3074
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Novel antiproliferative analogs of the Taq DNA polymerase inhibitor catalpol
Bioorganic and Medicinal Chemistry Letters, Vol. 17, Núm. 5, pp. 1332-1335