Publicacións en colaboración con investigadores/as de Hospital Universitario Nuestra Señora de Candelaria (20)

2018

  1. Lawsone, Juglone, and β-Lapachone Derivatives with Enhanced Mitochondrial-Based Toxicity

    ACS Chemical Biology, Vol. 13, Núm. 8, pp. 1950-1957

2017

  1. 5-Ethynylarylnaphthalimides as antitumor agents: Synthesis and biological evaluation

    Bioorganic and Medicinal Chemistry, Vol. 25, Núm. 6, pp. 1976-1983

  2. Synthesis and antibacterial activity of new symmetric polyoxygenated dibenzofurans

    European Journal of Medicinal Chemistry, Vol. 141, pp. 178-187

  3. Synthesis and biological evaluation of naphthoquinone-coumarin conjugates as topoisomerase II inhibitors

    Bioorganic and Medicinal Chemistry Letters, Vol. 27, Núm. 3, pp. 484-489

2016

  1. Domino Synthesis of Embelin Derivatives with Antibacterial Activity

    Journal of Natural Products, Vol. 79, Núm. 4, pp. 970-977

2015

  1. Structure and antimicrobial activity of phloroglucinol derivatives from achyrocline satureioides

    Journal of Natural Products, Vol. 78, Núm. 1, pp. 93-102

2014

  1. Yeast cytotoxic sensitivity to the antitumour agent β-lapachone depends mainly on oxidative stress and is largely independent of microtubule- or topoisomerase-mediated DNA damage

    Biochemical Pharmacology, Vol. 92, Núm. 2, pp. 206-219

2013

  1. Achyrofuran is an antibacterial agent capable of killing methicillin-resistant vancomycin-intermediate Staphylococcus aureus in the nanomolar range

    Phytomedicine, Vol. 20, Núm. 2, pp. 133-138

  2. Multicomponent synthesis of antibacterial dihydropyridin and dihydropyran embelin derivatives

    Journal of Organic Chemistry, Vol. 78, Núm. 16, pp. 7977-7985

  3. Synthesis and study of antiproliferative, antitopoisomerase II, DNA-intercalating and DNA-damaging activities of arylnaphthalimides

    Bioorganic and Medicinal Chemistry, Vol. 21, Núm. 21, pp. 6484-6495

2010

  1. Evaluation of labdane derivatives as potential anti-inflammatory agents

    European Journal of Medicinal Chemistry, Vol. 45, Núm. 7, pp. 3155-3161

  2. Synthesis and induction of apoptosis signaling pathway of ent-kaurane derivatives

    Bioorganic and Medicinal Chemistry, Vol. 18, Núm. 4, pp. 1724-1735

2009

  1. The lupane-type triterpene 30-oxo-calenduladiol is a CCR5 antagonist with anti-HIV-1 and anti-chemotactic activities

    Journal of Biological Chemistry, Vol. 284, Núm. 24, pp. 16609-16620

2008

  1. An efficient synthesis of embelin derivatives through domino Knoevenagel hetero Diels-Alder reactions under microwave irradiation

    Tetrahedron, Vol. 64, Núm. 37, pp. 8938-8942

  2. Design and synthesis of a novel series of pyranonaphthoquinones as topoisomerase II catalytic inhibitors

    Journal of Medicinal Chemistry, Vol. 51, Núm. 21, pp. 6761-6772

  3. New terpenoids from Maytenus apurimacensis as MDR reversal agents in the parasite Leishmania

    Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 3, pp. 1425-1430

  4. Structure and estrogenic activity of new lignans from Iryanthera lancifolia

    Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 6, pp. 3387-3394

2007

  1. Double domino Knoevenagel hetero Diels-Alder strategy towards bis-pyrano-1,4-benzoquinones

    Tetrahedron, Vol. 63, Núm. 14, pp. 3066-3074

2005

  1. Cheiloclines A-I. First examples of octacyclic sesquiterpene-triterpene hetero-Diels-Alder adducts

    Tetrahedron, Vol. 61, Núm. 2, pp. 429-436

  2. Synthesis of 9- and 10-membered macrolactones by selective ozonolysis of 1,4-diazaphenanthrene derivatives

    Tetrahedron, Vol. 61, Núm. 2, pp. 437-445