Publicaciones en colaboración con investigadores/as de Hospital Universitario de Canarias (163)

2024

  1. Efficient and safe therapeutic use of paired Cas9-nickases for primary hyperoxaluria type 1

    EMBO molecular medicine, Vol. 16, Núm. 1, pp. 112-131

  2. Inhibition of hepatic oxalate overproduction ameliorates metabolic dysfunction-associated steatohepatitis

    Nature Metabolism, Vol. 6, Núm. 10, pp. 1939-1962

  3. Insights into the pathogenesis of primary hyperoxaluria type I from the structural dynamics of alanine:glyoxylate aminotransferase variants

    FEBS Letters, Vol. 598, Núm. 4, pp. 485-499

  4. Modulation of the K/BxN arthritis mouse model and the effector functions of human fibroblast-like synoviocytes by liver X receptors

    European Journal of Immunology, Vol. 54, Núm. 11

  5. Postcolonoscopy colorectal cancer: Prevalence, categorization and root-cause analysis based on the World Endoscopic Organization system

    Gastroenterologia y Hepatologia, Vol. 47, Núm. 4, pp. 319-326

  6. Restored glyoxylate metabolism after AGXT gene correction and direct reprogramming of primary hyperoxaluria type 1 fibroblasts

    iScience, Vol. 27, Núm. 4

2023

  1. Beta human papillomavirus as a facilitator in the initial phase but not a perpetuator of skin carcinogenesis

    JEADV Clinical Practice

  2. Counterintuitive structural and functional effects due to naturally occurring mutations targeting the active site of the disease-associated NQO1 enzyme*

    FEBS Journal, Vol. 290, Núm. 7, pp. 1855-1873

  3. Determinants of Kidney Failure in Primary Hyperoxaluria Type 1: Findings of the European Hyperoxaluria Consortium

    Kidney International Reports, Vol. 8, Núm. 10, pp. 2029-2042

2022

  1. Allosteric Communication in the Multifunctional and Redox NQO1 Protein Studied by Cavity‐Making Mutations

    Antioxidants, Vol. 11, Núm. 6

  2. Atypical spindle cell lipomatous tumour presenting as a large retroperitoneal mass – a case report and review of the literature

    Polish Journal of Pathology, Vol. 73, Núm. 4, pp. 364-370

  3. Different phenotypic outcome due to site-specific phosphorylation in the cancer-associated NQO1 enzyme studied by phosphomimetic mutations

    Archives of Biochemistry and Biophysics, Vol. 729

  4. Effect of naturally-occurring mutations on the stability and function of cancer-associated NQO1: Comparison of experiments and computation

    Frontiers in Molecular Biosciences, Vol. 9

  5. Gastric metastases with a choriocarcinoma component from a postpuberal teratoma with mature histology

    Revista Espanola de Patologia, Vol. 55, pp. S49-S53

  6. Improved Outcome of Infantile Oxalosis Over Time in Europe: Data From the OxalEurope Registry

    Kidney International Reports, Vol. 7, Núm. 7, pp. 1608-1618

  7. In vivo CRISPR-Cas9 inhibition of hepatic LDH as treatment of primary hyperoxaluria

    Molecular Therapy - Methods and Clinical Development, Vol. 25, pp. 137-146

  8. Lactate dehydrogenase A inhibitors with a 2,8-dioxabicyclo[3.3.1]nonane scaffold: A contribution to molecular therapies for primary hyperoxalurias

    Bioorganic Chemistry, Vol. 129

  9. Molecular diagnosis in non-small-cell lung cancer: Expert opinion on ALK and ROS1 testing

    Journal of Clinical Pathology, Vol. 75, Núm. 3, pp. 145-153

  10. Phosphorylation of Thr9 Affects the Folding Landscape of the N-Terminal Segment of Human AGT Enhancing Protein Aggregation of Disease-Causing Mutants

    Molecules (Basel, Switzerland), Vol. 27, Núm. 24

  11. Targeting HIF-1α Function in Cancer through the Chaperone Action of NQO1: Implications of Genetic Diversity of NQO1

    Journal of Personalized Medicine, Vol. 12, Núm. 5