Miguel Xavier
Fernandes
Investigador no período 2013-2022
Universidade Do Porto
Oporto, PortugalPublicacións en colaboración con investigadores/as de Universidade Do Porto (10)
2016
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Optimizing the macrocyclic diterpenic core toward the reversal of multidrug resistance in cancer
Future Medicinal Chemistry, Vol. 8, Núm. 6, pp. 629-645
2013
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Discovery of a new small-molecule inhibitor of p53-MDM2 interaction using a yeast-based approach
Biochemical Pharmacology, Vol. 85, Núm. 9, pp. 1234-1245
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Sulfated small molecules targeting EBV in Burkitt lymphoma: From in silico screening to the evidence of in vitro effect on viral episomal DNA
Chemical Biology and Drug Design, Vol. 81, Núm. 5, pp. 631-644
2012
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Dual inhibitors of P-glycoprotein and tumor cell growth: (Re)discovering thioxanthones
Biochemical Pharmacology, Vol. 83, Núm. 1, pp. 57-68
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Enantioseparation and chiral recognition mechanism of new chiral derivatives of xanthones on macrocyclic antibiotic stationary phases
Journal of Chromatography A, Vol. 1241, pp. 60-68
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Multidrug resistance reversal effects of aminated thioxanthones and interaction with cytochrome P450 3A4
Journal of Pharmacy and Pharmaceutical Sciences, Vol. 15, Núm. 1, pp. 31-45
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Structure and Ligand-based design of P-glycoprotein inhibitors: A historical perspective
Current Pharmaceutical Design, Vol. 18, Núm. 27, pp. 4197-4214
2011
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New uses for old drugs: Pharmacophore-based screening for the discovery of P-glycoprotein inhibitors
Chemical Biology and Drug Design, Vol. 78, Núm. 1, pp. 57-72
2010
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Insights into the in vitro antitumor mechanism of action of a new pyranoxanthone
Chemical Biology and Drug Design, Vol. 76, Núm. 1, pp. 43-58
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Pharmacophore-Based Screening as a Clue for the Discovery of New P-Glycoprotein Inhibitors
ADVANCES IN BIOINFORMATICS