Publicaciones (68) Publicaciones de Miguel Xavier Fernandes

2023

  1. Conformationally Restricted Glycoconjugates Derived from Arylsulfonamides and Coumarins: New Families of Tumour-Associated Carbonic Anhydrase Inhibitors

    International Journal of Molecular Sciences, Vol. 24, Núm. 11

  2. Investigation of the enantioselectivity of acetylcholinesterase and butyrylcholinesterase upon inhibition by tacrine-iminosugar heterodimers

    Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 38, Núm. 1, pp. 349-360

2022

  1. 2-Aminobenzoxazole-appended coumarins as potent and selective inhibitors of tumour-associated carbonic anhydrases

    Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 37, Núm. 1, pp. 168-177

  2. A Comprehensive Evaluation of Sdox, a Promising H2S-Releasing Doxorubicin for the Treatment of Chemoresistant Tumors

    Frontiers in Pharmacology, Vol. 13

  3. A hybrid of 1-deoxynojirimycin and benzotriazole induces preferential inhibition of butyrylcholinesterase (BuChE) over acetylcholinesterase (AChE)

    Journal of enzyme inhibition and medicinal chemistry, Vol. 37, Núm. 1, pp. 2395-2402

  4. Carbohydrate-derived bicyclic selenazolines as new dual inhibitors (cholinesterases/OGA) against Alzheimer's disease

    Bioorganic Chemistry, Vol. 127

  5. Lactate dehydrogenase A inhibitors with a 2,8-dioxabicyclo[3.3.1]nonane scaffold: A contribution to molecular therapies for primary hyperoxalurias

    Bioorganic Chemistry, Vol. 129

  6. New salicylic acid derivatives, double inhibitors of glycolate oxidase and lactate dehydrogenase, as effective agents decreasing oxalate production

    European Journal of Medicinal Chemistry, Vol. 237

  7. Squaramide-Tethered Sulfonamides and Coumarins: Synthesis, Inhibition of Tumor-Associated CAs IX and XII and Docking Simulations

    International Journal of Molecular Sciences, Vol. 23, Núm. 14

2021

  1. Small molecule-based enzyme inhibitors in the treatment of primary hyperoxalurias

    Journal of Personalized Medicine, Vol. 11, Núm. 2, pp. 1-31

  2. Tuning the activity of iminosugars: novel N-alkylated deoxynojirimycin derivatives as strong BuChE inhibitors

    Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 36, Núm. 1, pp. 138-146

2020

  1. CKT0353, a novel microtubule targeting agent, overcomes paclitaxel induced resistance in cancer cells

    Investigational New Drugs, Vol. 38, Núm. 3, pp. 584-598

2019

  1. Effects of hydroxycinnamic acids on the glycolysis pathway

    South African Journal of Botany, Vol. 120, pp. 219-229

  2. Inhibition of the mTOR pathway: A new mechanism of β cell toxicity induced by tacrolimus

    American Journal of Transplantation, Vol. 19, Núm. 12, pp. 3240-3249

  3. Prediction of terpenoid toxicity based on a quantitative structure–activity relationship model

    Foods, Vol. 8, Núm. 12

  4. Selenocoumarins as new multitarget antiproliferative agents: Synthesis, biological evaluation and in silico calculations

    European Journal of Medicinal Chemistry, Vol. 179, pp. 493-501

2018

  1. Anti-Proliferative 1,4-Dihydropyridine and Pyridine Derivatives Synthesized through a Catalyst-Free, One-Pot Multi-Component Reaction

    ChemistrySelect, Vol. 3, Núm. 43, pp. 12163-12168

  2. Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type 1

    Journal of Medicinal Chemistry, Vol. 61, Núm. 16, pp. 7144-7167

2017

  1. DTA0100, dual topoisomerase II and microtubule inhibitor, evades paclitaxel resistance in P-glycoprotein overexpressing cancer cells

    European Journal of Pharmaceutical Sciences, Vol. 105, pp. 159-168

2016

  1. Optimizing the macrocyclic diterpenic core toward the reversal of multidrug resistance in cancer

    Future Medicinal Chemistry, Vol. 8, Núm. 6, pp. 629-645