![Foto de Miguel Xavier](/img/nophoto.png)
Miguel Xavier
Fernandes
Investigador en el periodo 2013-2022
Publicaciones (70) Publicaciones de Miguel Xavier Fernandes
2024
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Coumarin-azasugar-benzyl conjugates as non-neurotoxic dual inhibitors of butyrylcholinesterase and cancer cell growth
Organic & biomolecular chemistry, Vol. 22, Núm. 17, pp. 3425-3438
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Modelling the pH dependent retention and competitive adsorption of charged and ionizable solutes in mixed-mode and reversed-phase liquid chromatography
Journal of Chromatography A, Vol. 1730
2023
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Conformationally Restricted Glycoconjugates Derived from Arylsulfonamides and Coumarins: New Families of Tumour-Associated Carbonic Anhydrase Inhibitors
International Journal of Molecular Sciences, Vol. 24, Núm. 11
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Investigation of the enantioselectivity of acetylcholinesterase and butyrylcholinesterase upon inhibition by tacrine-iminosugar heterodimers
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 38, Núm. 1, pp. 349-360
2022
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2-Aminobenzoxazole-appended coumarins as potent and selective inhibitors of tumour-associated carbonic anhydrases
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 37, Núm. 1, pp. 168-177
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A Comprehensive Evaluation of Sdox, a Promising H2S-Releasing Doxorubicin for the Treatment of Chemoresistant Tumors
Frontiers in Pharmacology, Vol. 13
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A hybrid of 1-deoxynojirimycin and benzotriazole induces preferential inhibition of butyrylcholinesterase (BuChE) over acetylcholinesterase (AChE)
Journal of enzyme inhibition and medicinal chemistry, Vol. 37, Núm. 1, pp. 2395-2402
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Carbohydrate-derived bicyclic selenazolines as new dual inhibitors (cholinesterases/OGA) against Alzheimer's disease
Bioorganic Chemistry, Vol. 127
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Lactate dehydrogenase A inhibitors with a 2,8-dioxabicyclo[3.3.1]nonane scaffold: A contribution to molecular therapies for primary hyperoxalurias
Bioorganic Chemistry, Vol. 129
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New salicylic acid derivatives, double inhibitors of glycolate oxidase and lactate dehydrogenase, as effective agents decreasing oxalate production
European Journal of Medicinal Chemistry, Vol. 237
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Squaramide-Tethered Sulfonamides and Coumarins: Synthesis, Inhibition of Tumor-Associated CAs IX and XII and Docking Simulations
International Journal of Molecular Sciences, Vol. 23, Núm. 14
2021
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Small molecule-based enzyme inhibitors in the treatment of primary hyperoxalurias
Journal of Personalized Medicine, Vol. 11, Núm. 2, pp. 1-31
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Tuning the activity of iminosugars: novel N-alkylated deoxynojirimycin derivatives as strong BuChE inhibitors
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 36, Núm. 1, pp. 138-146
2020
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CKT0353, a novel microtubule targeting agent, overcomes paclitaxel induced resistance in cancer cells
Investigational New Drugs, Vol. 38, Núm. 3, pp. 584-598
2019
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Effects of hydroxycinnamic acids on the glycolysis pathway
South African Journal of Botany, Vol. 120, pp. 219-229
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Inhibition of the mTOR pathway: A new mechanism of β cell toxicity induced by tacrolimus
American Journal of Transplantation, Vol. 19, Núm. 12, pp. 3240-3249
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Prediction of terpenoid toxicity based on a quantitative structure–activity relationship model
Foods, Vol. 8, Núm. 12
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Selenocoumarins as new multitarget antiproliferative agents: Synthesis, biological evaluation and in silico calculations
European Journal of Medicinal Chemistry, Vol. 179, pp. 493-501
2018
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Anti-Proliferative 1,4-Dihydropyridine and Pyridine Derivatives Synthesized through a Catalyst-Free, One-Pot Multi-Component Reaction
ChemistrySelect, Vol. 3, Núm. 43, pp. 12163-12168
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Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type 1
Journal of Medicinal Chemistry, Vol. 61, Núm. 16, pp. 7144-7167