![Foto de Aravind Singh](/img/nophoto.png)
Aravind Singh
Kshatri
Researcher in the period 2016-2022
Publications (11) Aravind Singh Kshatri publications
2024
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Discovery of a novel and highly selective JAK3 inhibitor as a potent hair growth promoter
Journal of Translational Medicine, Vol. 22, Núm. 1
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Identification of a novel GSK3β inhibitor involved in abrogating KRas dependent pancreatic tumors in Wnt/beta-catenin and NF-kB dependent manner
Life Sciences, Vol. 351
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Subunit-specific inhibition of BK channels by piperine
Biophysical Journal, Vol. 123, Núm. 14, pp. 1942-1953
2021
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Calcium-activated potassium channels
Calcium Signals: From single molecules to physiology (Institute of Physics Publishing), pp. 6-1-6-28
2020
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Differential regulation of BK channels by fragile X mental retardation protein
Journal of General Physiology, Vol. 152, Núm. 6
2018
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Functional validation of Ca2 +-binding residues from the crystal structure of the BK ion channel
Biochimica et Biophysica Acta - Biomembranes, Vol. 1860, Núm. 4, pp. 943-952
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Physiological Roles and Therapeutic Potential of Ca2+ Activated Potassium Channels in the Nervous System
Frontiers in Molecular Neuroscience, Vol. 11
2017
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Differential efficacy of GoSlo-SR compounds on BKα and BKαγ1–4 channels
Channels, Vol. 11, Núm. 1, pp. 66-78
2015
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Effects of the novel BK (KCa1.1) channel opener GoSlo-SR-5-130 are dependent on the presence of BKβ subunits
British Journal of Pharmacology, Vol. 172, Núm. 10, pp. 2544-2556
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Molecular mechanisms underlying the effect of the novel BK channel opener GoSlo: Involvement of the S4/S5 linker and the S6 segment
Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Núm. 7, pp. 2064-2069
2014
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Development of GoSlo-SR-5-69, a potent activator of large conductance Ca2+-activated K+ (BK) channels
European Journal of Medicinal Chemistry, Vol. 75, pp. 426-437