Ciencias Médicas Básicas
Department
Cristina
Martín Higueras
Researcher in the period 2020-2022
Publications by the researcher in collaboration with Cristina Martín Higueras (11)
2023
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Determinants of Kidney Failure in Primary Hyperoxaluria Type 1: Findings of the European Hyperoxaluria Consortium
Kidney International Reports, Vol. 8, Núm. 10, pp. 2029-2042
2022
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New salicylic acid derivatives, double inhibitors of glycolate oxidase and lactate dehydrogenase, as effective agents decreasing oxalate production
European Journal of Medicinal Chemistry, Vol. 237
2019
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Systemic Alanine Glyoxylate Aminotransferase mRNA Improves Glyoxylate Metabolism in a Mouse Model of Primary Hyperoxaluria Type 1
Nucleic Acid Therapeutics, Vol. 29, Núm. 2, pp. 104-113
2018
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CRISPR/Cas9-mediated glycolate oxidase disruption is an efficacious and safe treatment for primary hyperoxaluria type I
Nature Communications, Vol. 9, Núm. 1
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Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type 1
Journal of Medicinal Chemistry, Vol. 61, Núm. 16, pp. 7144-7167
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Specific Inhibition of Hepatic Lactate Dehydrogenase Reduces Oxalate Production in Mouse Models of Primary Hyperoxaluria
Molecular Therapy, Vol. 26, Núm. 8, pp. 1983-1995
2017
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Molecular therapy in primary hyperoxaluria type 1
Molecular therapy in primary hyperoxaluria type 1
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Molecular therapy of primary hyperoxaluria
Journal of Inherited Metabolic Disease, Vol. 40, Núm. 4, pp. 481-489
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siRNA therapeutics to treat liver disorders
Safety and Efficacy of Gene-Based Therapeutics for Inherited Disorders (Springer International Publishing), pp. 159-190
2016
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Glycolate oxidase is a safe and efficient target for substrate reduction therapy in a mouse model of primary hyperoxaluria Type I
Molecular Therapy, Vol. 24, Núm. 4, pp. 719-725
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Iohexol plasma clearance, a simple and reliable method to measure renal function in conscious mice
Pflugers Archiv European Journal of Physiology, Vol. 468, Núm. 9, pp. 1587-1594