Publications by the researcher in collaboration with Juan Luis Pacheco García (8)

2024

  1. Insights into the pathogenesis of primary hyperoxaluria type I from the structural dynamics of alanine:glyoxylate aminotransferase variants

    FEBS Letters, Vol. 598, Núm. 4, pp. 485-499

2023

  1. Counterintuitive structural and functional effects due to naturally occurring mutations targeting the active site of the disease-associated NQO1 enzyme*

    FEBS Journal, Vol. 290, Núm. 7, pp. 1855-1873

2022

  1. Allosteric Communication in the Multifunctional and Redox NQO1 Protein Studied by Cavity‐Making Mutations

    Antioxidants, Vol. 11, Núm. 6

  2. Different phenotypic outcome due to site-specific phosphorylation in the cancer-associated NQO1 enzyme studied by phosphomimetic mutations

    Archives of Biochemistry and Biophysics, Vol. 729

  3. Effect of naturally-occurring mutations on the stability and function of cancer-associated NQO1: Comparison of experiments and computation

    Frontiers in Molecular Biosciences, Vol. 9

  4. Targeting HIF-1α Function in Cancer through the Chaperone Action of NQO1: Implications of Genetic Diversity of NQO1

    Journal of Personalized Medicine, Vol. 12, Núm. 5

2021

  1. Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue

    Redox Biology, Vol. 46

2020

  1. Naturally-occurring rare mutations cause mild to catastrophic effects in the multifunctional and cancer-associated NQO1 protein

    Journal of Personalized Medicine, Vol. 10, Núm. 4, pp. 1-31