Química Orgánica
Département
Leandro Francisco
Fernández Pérez
Publications dans lesquelles il/elle collabore avec Leandro Francisco Fernández Pérez (18)
2022
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Design, Semisynthesis, and Estrogenic Activity of Lignan Derivatives from Natural Dibenzylbutyrolactones
Pharmaceuticals, Vol. 15, Núm. 5, pp. 585
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Discovery of Highly Functionalized 5-hydroxy-2H-pyrrol-2-ones That Exhibit Antiestrogenic Effects in Breast and Endometrial Cancer Cells and Potentiate the Antitumoral Effect of Tamoxifen
Cancers, Vol. 14, Núm. 21
2021
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JKST6, a novel multikinase modulator of the BCR-ABL1/STAT5 signaling pathway that potentiates direct BCR-ABL1 inhibition and overcomes imatinib resistance in chronic myelogenous leukemia
Biomedicine and Pharmacotherapy, Vol. 144
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Modular synthesis and antiproliferative activity of new dihydro-1H-pyrazolo[1,3-b]pyridine embelin derivatives
Pharmaceuticals, Vol. 14, Núm. 10
2019
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A novel naphthoquinone-coumarin hybrid that inhibits BCR-ABL1-STAT5 oncogenic pathway and reduces survival in imatinib-resistant chronic myelogenous leukemia cells
Frontiers in Pharmacology, Vol. 9, Núm. JAN
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Signal transducer and activator of transcription (STAT)-5: an opportunity for drug development in oncohematology
Oncogene, Vol. 38, Núm. 24, pp. 4657-4668
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Synthesis and antiplasmodial activity of 1,2,3-triazole-naphthoquinone conjugates
Molecules, Vol. 24, Núm. 21
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Synthesis, characterization and antiproliferative activity of mixed ligand complexes of Cu2+ and Co2+ with lapachol
Polyhedron, Vol. 165, pp. 73-78
2018
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Correction: CM363, a novel naphthoquinone derivative which acts as multikinase modulator and overcomes imatinib resistance in chronic myelogenous leukemia [Oncotarget, 8 (2017) (29679-29698)] Doi: 10.18632/oncotarget.11425
Oncotarget
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Lawsone, Juglone, and β-Lapachone Derivatives with Enhanced Mitochondrial-Based Toxicity
ACS Chemical Biology, Vol. 13, Núm. 8, pp. 1950-1957
2017
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5-Ethynylarylnaphthalimides as antitumor agents: Synthesis and biological evaluation
Bioorganic and Medicinal Chemistry, Vol. 25, Núm. 6, pp. 1976-1983
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CM363, a novel naphthoquinone derivative which acts as multikinase modulator and overcomes imatinib resistance in chronic myelogenous leukemia
Oncotarget, Vol. 8, Núm. 18, pp. 29679-29698
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In vitro activity of 1H-phenalen-1-one derivatives against Acanthamoeba castellanii Neff and their mechanisms of cell death
Experimental Parasitology, Vol. 183, pp. 218-223
2015
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Synthesis of 4,4′-Diaminotriphenylmethanes with Potential Selective Estrogen Receptor Modulator (SERM)-like Activity
ChemMedChem, Vol. 10, Núm. 8, pp. 1403-1412
2014
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Indium catalyzed solvent-free multicomponent synthesis of cytotoxic dibenzo[a,h]anthracenes from aldehydes, 2-hydroxy-1,4-naphthoquinone, and 2-naphthol
Tetrahedron, Vol. 70, Núm. 45, pp. 8480-8487
2013
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Synthesis and study of antiproliferative, antitopoisomerase II, DNA-intercalating and DNA-damaging activities of arylnaphthalimides
Bioorganic and Medicinal Chemistry, Vol. 21, Núm. 21, pp. 6484-6495
2010
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Cytotoxic triterpenoids from Maytenus retusa
Journal of Natural Products, Vol. 73, Núm. 12, pp. 2029-2034
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Synthesis and in vitro antiprotozoal evaluation of substituted phenalenone analogues
Bioorganic and Medicinal Chemistry, Vol. 18, Núm. 12, pp. 4530-4534