Química Orgánica
Departamento
Instituto Canario de Investigación del Cáncer
Santa Cruz de Tenerife, EspañaPublicacions en col·laboració amb investigadors/es de Instituto Canario de Investigación del Cáncer (65)
2017
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Bioactive diterpenoids from Celastraceae species
Phytochemistry Reviews, Vol. 16, Núm. 5, pp. 861-881
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CM363, a novel naphthoquinone derivative which acts as multikinase modulator and overcomes imatinib resistance in chronic myelogenous leukemia
Oncotarget, Vol. 8, Núm. 18, pp. 29679-29698
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Structure-based design, synthesis, and biological evaluation of withaferin A-analogues as potent apoptotic inducers
European Journal of Medicinal Chemistry, Vol. 140, pp. 52-64
2016
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Absolute Configuration of Dihydro-β-agarofuran Sesquiterpenes from Maytenus jelskii and Their Potential Antitumor-Promoting Effects
Journal of Natural Products, Vol. 79, Núm. 9, pp. 2324-2331
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Optimization by Molecular Fine Tuning of Dihydro-β-agarofuran Sesquiterpenoids as Reversers of P-Glycoprotein-Mediated Multidrug Resistance
Journal of Medicinal Chemistry, Vol. 59, Núm. 5, pp. 1880-1890
2015
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Random laser in biological tissues impregnated with a fluorescent anticancer drug
Laser Physics Letters, Vol. 12, Núm. 4
2014
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A new family of choline kinase inhibitors with antiproliferative and antitumor activity derived from natural products
Clinical and Translational Oncology, Vol. 17, Núm. 1, pp. 74-84
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Yeast cytotoxic sensitivity to the antitumour agent β-lapachone depends mainly on oxidative stress and is largely independent of microtubule- or topoisomerase-mediated DNA damage
Biochemical Pharmacology, Vol. 92, Núm. 2, pp. 206-219
2013
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Achyrofuran is an antibacterial agent capable of killing methicillin-resistant vancomycin-intermediate Staphylococcus aureus in the nanomolar range
Phytomedicine, Vol. 20, Núm. 2, pp. 133-138
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Multicomponent synthesis of antibacterial dihydropyridin and dihydropyran embelin derivatives
Journal of Organic Chemistry, Vol. 78, Núm. 16, pp. 7977-7985
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Preparation and antimalarial activity of semisynthetic lycorenine derivatives
European Journal of Medicinal Chemistry, Vol. 63, pp. 722-730
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Synthesis and cytotoxic activity of metallic complexes of lawsone
Bioorganic and Medicinal Chemistry, Vol. 21, Núm. 9, pp. 2471-2477
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Synthesis and study of antiproliferative, antitopoisomerase II, DNA-intercalating and DNA-damaging activities of arylnaphthalimides
Bioorganic and Medicinal Chemistry, Vol. 21, Núm. 21, pp. 6484-6495
2012
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Antiproliferative activity of withanolide derivatives from Jaborosa cabrerae and Jaborosa reflexa. Chemotaxonomic considerations
Phytochemistry, Vol. 76, pp. 150-157
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Labdanolic acid methyl ester (LAME) exerts anti-inflammatory effects through inhibition of TAK-1 activation
Toxicology and Applied Pharmacology, Vol. 258, Núm. 1, pp. 109-117
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Synthesis and anti-HIV activity of lupane and olean-18-ene derivatives. Absolute configuration of 19,20-epoxylupanes by VCD
Journal of Natural Products, Vol. 75, Núm. 4, pp. 669-676
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Synthesis and antimalarial activity of new haemanthamine-type derivatives
Bioorganic and Medicinal Chemistry, Vol. 20, Núm. 18, pp. 5464-5472
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Unexpected domino synthesis of complex angular naphthoimidazoles
European Journal of Organic Chemistry, pp. 5757-5766
2011
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Benzodihydrofurans from Cyperus teneriffae
Journal of Natural Products, Vol. 74, Núm. 5, pp. 1061-1065
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Dihydro-β-agarofuran sesquiterpenoids from Plenckia integerrima
Planta Medica, Vol. 77, Núm. 15, pp. 1718-1724