Química Orgánica
Département
Universidad de Las Palmas de Gran Canaria
Las Palmas de Gran Canaria, EspañaPublications en collaboration avec des chercheurs de Universidad de Las Palmas de Gran Canaria (34)
2022
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Alciporin, a pore-forming protein as complementary defense mechanism in Millepora alcicornis
Frontiers in Marine Science, Vol. 9
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Discovery of Highly Functionalized 5-hydroxy-2H-pyrrol-2-ones That Exhibit Antiestrogenic Effects in Breast and Endometrial Cancer Cells and Potentiate the Antitumoral Effect of Tamoxifen
Cancers, Vol. 14, Núm. 21
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Guanidine Derivatives Containing the Chalcone Skeleton Are Potent Antiproliferative Compounds against Human Leukemia Cells
International journal of molecular sciences, Vol. 23, Núm. 24
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Metabolic Hepatic Disorders Caused by Ciguatoxins in Goldfish (Carassius auratus)
Animals, Vol. 12, Núm. 24
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Structure-activity relationships reveal a 2-furoyloxychalcone as a potent cytotoxic and apoptosis inducer for human U-937 and HL-60 leukaemia cells
Bioorganic Chemistry, Vol. 127
2021
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JKST6, a novel multikinase modulator of the BCR-ABL1/STAT5 signaling pathway that potentiates direct BCR-ABL1 inhibition and overcomes imatinib resistance in chronic myelogenous leukemia
Biomedicine and Pharmacotherapy, Vol. 144
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Modular synthesis and antiproliferative activity of new dihydro-1H-pyrazolo[1,3-b]pyridine embelin derivatives
Pharmaceuticals, Vol. 14, Núm. 10
2020
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Efficient Multicomponent Synthesis of Diverse Antibacterial Embelin-Privileged Structure Conjugates
Molecules (Basel, Switzerland), Vol. 25, Núm. 14
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The synthetic flavanone 6-methoxy-2-(naphthalen-1-yl)chroman-4-one induces apoptosis and activation of the MAPK pathway in human U-937 leukaemia cells
Bioorganic Chemistry, Vol. 94
2019
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A novel naphthoquinone-coumarin hybrid that inhibits BCR-ABL1-STAT5 oncogenic pathway and reduces survival in imatinib-resistant chronic myelogenous leukemia cells
Frontiers in Pharmacology, Vol. 9, Núm. JAN
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Signal transducer and activator of transcription (STAT)-5: an opportunity for drug development in oncohematology
Oncogene, Vol. 38, Núm. 24, pp. 4657-4668
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Synthesis and antiplasmodial activity of 1,2,3-triazole-naphthoquinone conjugates
Molecules, Vol. 24, Núm. 21
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Synthesis, characterization and antiproliferative activity of mixed ligand complexes of Cu2+ and Co2+ with lapachol
Polyhedron, Vol. 165, pp. 73-78
2018
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3′-Hydroxy-3,4′-dimethoxyflavone-induced cell death in human leukaemia cells is dependent on caspases and reactive oxygen species and attenuated by the inhibition of JNK/SAPK
Chemico-Biological Interactions, Vol. 288, pp. 1-11
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Correction: CM363, a novel naphthoquinone derivative which acts as multikinase modulator and overcomes imatinib resistance in chronic myelogenous leukemia [Oncotarget, 8 (2017) (29679-29698)] Doi: 10.18632/oncotarget.11425
Oncotarget
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Lawsone, Juglone, and β-Lapachone Derivatives with Enhanced Mitochondrial-Based Toxicity
ACS Chemical Biology, Vol. 13, Núm. 8, pp. 1950-1957
2017
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3′-Hydroxy-3,4′-dimethoxyflavone blocks tubulin polymerization and is a potent apoptotic inducer in human SK-MEL-1 melanoma cells
Bioorganic and Medicinal Chemistry, Vol. 25, Núm. 21, pp. 6060-6070
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5-Ethynylarylnaphthalimides as antitumor agents: Synthesis and biological evaluation
Bioorganic and Medicinal Chemistry, Vol. 25, Núm. 6, pp. 1976-1983
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CM363, a novel naphthoquinone derivative which acts as multikinase modulator and overcomes imatinib resistance in chronic myelogenous leukemia
Oncotarget, Vol. 8, Núm. 18, pp. 29679-29698
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In vitro activity of 1H-phenalen-1-one derivatives against Acanthamoeba castellanii Neff and their mechanisms of cell death
Experimental Parasitology, Vol. 183, pp. 218-223