Instituto Universitario de Bio-Orgánica Antonio González
Ikerketa institutua
University of Massachusetts Medical School
Worcester, Estados UnidosUniversity of Massachusetts Medical School-ko ikertzaileekin lankidetzan egindako argitalpenak (4)
2009
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Toward the design of mutation-resistant enzyme inhibitors: Further evaluation of the substrate envelope hypothesis
Chemical Biology and Drug Design, Vol. 74, Núm. 3, pp. 234-245
2008
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HIV-1 protease inhibitors from inverse design in the substrate envelope exhibit subnanomolar binding to drug-resistant variants
Journal of the American Chemical Society, Vol. 130, Núm. 19, pp. 6099-6113
2007
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Design of mutation-resistant HIV protease inhibitors with the substrate envelope hypothesis
Chemical Biology and Drug Design, Vol. 69, Núm. 5, pp. 298-313
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Evaluation of the substrate envelope hypothesis for inhibitors of HIV-1 protease
Proteins: Structure, Function and Genetics, Vol. 68, Núm. 2, pp. 561-567