Instituto Universitario de Bio-Orgánica Antonio González
Institut de recherche
Instituto Canario de Investigación del Cáncer
Santa Cruz de Tenerife, EspañaPublications en collaboration avec des chercheurs de Instituto Canario de Investigación del Cáncer (60)
2022
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Guanidine Derivatives Containing the Chalcone Skeleton Are Potent Antiproliferative Compounds against Human Leukemia Cells
International journal of molecular sciences, Vol. 23, Núm. 24
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Structure-activity relationships reveal a 2-furoyloxychalcone as a potent cytotoxic and apoptosis inducer for human U-937 and HL-60 leukaemia cells
Bioorganic Chemistry, Vol. 127
2017
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Bioactive diterpenoids from Celastraceae species
Phytochemistry Reviews, Vol. 16, Núm. 5, pp. 861-881
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CM363, a novel naphthoquinone derivative which acts as multikinase modulator and overcomes imatinib resistance in chronic myelogenous leukemia
Oncotarget, Vol. 8, Núm. 18, pp. 29679-29698
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Structure-based design, synthesis, and biological evaluation of withaferin A-analogues as potent apoptotic inducers
European Journal of Medicinal Chemistry, Vol. 140, pp. 52-64
2016
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Absolute Configuration of Dihydro-β-agarofuran Sesquiterpenes from Maytenus jelskii and Their Potential Antitumor-Promoting Effects
Journal of Natural Products, Vol. 79, Núm. 9, pp. 2324-2331
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Optimization by Molecular Fine Tuning of Dihydro-β-agarofuran Sesquiterpenoids as Reversers of P-Glycoprotein-Mediated Multidrug Resistance
Journal of Medicinal Chemistry, Vol. 59, Núm. 5, pp. 1880-1890
2014
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A new family of choline kinase inhibitors with antiproliferative and antitumor activity derived from natural products
Clinical and Translational Oncology, Vol. 17, Núm. 1, pp. 74-84
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Yeast cytotoxic sensitivity to the antitumour agent β-lapachone depends mainly on oxidative stress and is largely independent of microtubule- or topoisomerase-mediated DNA damage
Biochemical Pharmacology, Vol. 92, Núm. 2, pp. 206-219
2013
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Achyrofuran is an antibacterial agent capable of killing methicillin-resistant vancomycin-intermediate Staphylococcus aureus in the nanomolar range
Phytomedicine, Vol. 20, Núm. 2, pp. 133-138
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Multicomponent synthesis of antibacterial dihydropyridin and dihydropyran embelin derivatives
Journal of Organic Chemistry, Vol. 78, Núm. 16, pp. 7977-7985
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Preparation and antimalarial activity of semisynthetic lycorenine derivatives
European Journal of Medicinal Chemistry, Vol. 63, pp. 722-730
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Synthesis and cytotoxic activity of metallic complexes of lawsone
Bioorganic and Medicinal Chemistry, Vol. 21, Núm. 9, pp. 2471-2477
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Synthesis and study of antiproliferative, antitopoisomerase II, DNA-intercalating and DNA-damaging activities of arylnaphthalimides
Bioorganic and Medicinal Chemistry, Vol. 21, Núm. 21, pp. 6484-6495
2012
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Antiproliferative activity of withanolide derivatives from Jaborosa cabrerae and Jaborosa reflexa. Chemotaxonomic considerations
Phytochemistry, Vol. 76, pp. 150-157
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Labdanolic acid methyl ester (LAME) exerts anti-inflammatory effects through inhibition of TAK-1 activation
Toxicology and Applied Pharmacology, Vol. 258, Núm. 1, pp. 109-117
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Synthesis and anti-HIV activity of lupane and olean-18-ene derivatives. Absolute configuration of 19,20-epoxylupanes by VCD
Journal of Natural Products, Vol. 75, Núm. 4, pp. 669-676
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Synthesis and antimalarial activity of new haemanthamine-type derivatives
Bioorganic and Medicinal Chemistry, Vol. 20, Núm. 18, pp. 5464-5472
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Unexpected domino synthesis of complex angular naphthoimidazoles
European Journal of Organic Chemistry, pp. 5757-5766
2011
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Benzodihydrofurans from Cyperus teneriffae
Journal of Natural Products, Vol. 74, Núm. 5, pp. 1061-1065