Instituto Universitario de Bio-Orgánica Antonio González
Forschungsinstitut
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Universidad de Sevilla
Sevilla, EspañaPublikationen in Zusammenarbeit mit Forschern von Universidad de Sevilla (31)
2024
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Coumarin-azasugar-benzyl conjugates as non-neurotoxic dual inhibitors of butyrylcholinesterase and cancer cell growth
Organic & biomolecular chemistry, Vol. 22, Núm. 17, pp. 3425-3438
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Coumarins-lipophilic cations conjugates: Efficient mitocans targeting carbonic anhydrases
Bioorganic Chemistry, Vol. 145
2023
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Biotinylated selenocyanates: Potent and selective cytostatic agents
Bioorganic Chemistry, Vol. 133
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Conformationally Restricted Glycoconjugates Derived from Arylsulfonamides and Coumarins: New Families of Tumour-Associated Carbonic Anhydrase Inhibitors
International Journal of Molecular Sciences, Vol. 24, Núm. 11
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Fluoro-labelled sp2-iminoglycolipids with immunomodulatory properties
European Journal of Medicinal Chemistry, Vol. 255
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Investigation of the enantioselectivity of acetylcholinesterase and butyrylcholinesterase upon inhibition by tacrine-iminosugar heterodimers
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 38, Núm. 1, pp. 349-360
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N-Substituted 3-Aminooxindoles and N-Propargyl Derivatives: Potential Biological Activities against Alzheimer's Disease
Results in Chemistry, Vol. 6
2022
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2-Aminobenzoxazole-appended coumarins as potent and selective inhibitors of tumour-associated carbonic anhydrases
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 37, Núm. 1, pp. 168-177
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A hybrid of 1-deoxynojirimycin and benzotriazole induces preferential inhibition of butyrylcholinesterase (BuChE) over acetylcholinesterase (AChE)
Journal of enzyme inhibition and medicinal chemistry, Vol. 37, Núm. 1, pp. 2395-2402
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Carbohydrate-derived bicyclic selenazolines as new dual inhibitors (cholinesterases/OGA) against Alzheimer's disease
Bioorganic Chemistry, Vol. 127
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Chemoselective Preparation of New Families of Phenolic-Organoselenium Hybrids—A Biological Assessment
Molecules, Vol. 27, Núm. 4
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Iridium-and Palladium-Based Catalysts in the Pharmaceutical Industry
Catalysts, Vol. 12, Núm. 2
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Squaramide-Tethered Sulfonamides and Coumarins: Synthesis, Inhibition of Tumor-Associated CAs IX and XII and Docking Simulations
International Journal of Molecular Sciences, Vol. 23, Núm. 14
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Straightforward access to novel mitochondriotropics derived from 2-arylethanol as potent and selective antiproliferative agents
European Journal of Medicinal Chemistry, Vol. 228
2021
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Novel 1,2,3-triazole epicinchonas: Transitioning from organocatalysis to biological activities
Synthetic Communications, Vol. 51, Núm. 19, pp. 2954-2974
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Synthesis of sp2-Iminosugar Selenoglycolipids as Multitarget Drug Candidates with Antiproliferative, Leishmanicidal and Anti-Inflammatory Properties
Molecules (Basel, Switzerland), Vol. 26, Núm. 24
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Tuning the activity of iminosugars: novel N-alkylated deoxynojirimycin derivatives as strong BuChE inhibitors
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 36, Núm. 1, pp. 138-146
2020
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Masked phenolic-selenium conjugates: Potent and selective antiproliferative agents overcoming p-gp resistance
Pharmaceuticals, Vol. 13, Núm. 11, pp. 1-22
2019
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Selenocoumarins as new multitarget antiproliferative agents: Synthesis, biological evaluation and in silico calculations
European Journal of Medicinal Chemistry, Vol. 179, pp. 493-501
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Synthesis of polyfluoroalkyl sp2-iminosugar glycolipids and evaluation of their immunomodulatory properties towards anti-tumor, anti-leishmanial and anti-inflammatory therapies
European Journal of Medicinal Chemistry, Vol. 182