Development of analytical methodologies for the determination of compounds with oestrogenic activity

  1. Bárbara Socas Rodríguez
Supervised by:
  1. Miguel Ángel Rodríguez Delgado Director
  2. Javier Hernández Borges Director

Defence university: Universidad de La Laguna

Fecha de defensa: 14 July 2017

  1. Marta Lores Chair
  2. Luis Rafael Galindo Martín Secretary
  3. José Manuel F. Nogueira Committee member
  1. Química

Type: Thesis

Teseo: 490873 DIALNET lock_openRIULL editor


In this PhD Thesis, different sensitive and environmentally friendly analytical methodologies have been developed for the analysis of a wide group of oestrogenic compounds in environmental and food samples of diverse nature. With this aim, selective extraction techniques, including hollow-fibre liquid-phase microextraction, dispersive liquid-liquid microextraction using ionic liquids, the QuEChERS method and magnetic and non-magnetic micro-dipersive solid-phase extraction using diverse nanomaterials, have been applied. These procedures have been combined with different liquid chromatographic systems such as high-performance liquid chromatography and ultra-high-performance liquid chromatography for the separation and determination of the target compounds using diode array, fluorescence and tandem mass spectrometry detectors.