Combinación de la anhidrasa carbónica tópica y sistémica en el tratamiento de la retinosquisis ligada al cromosoma X

  1. Pedro Rocha Cabrera
  2. Alicia Cristina Pareja Ríos
  3. L. M. Cordovés Dorta
  4. C. Mantolán Sarmiento
  5. Miguel Ángel Serrano García
Archivos de la Sociedad Española de Oftalmologia

ISSN: 0365-6691

Year of publication: 2014

Volume: 89

Issue: 8

Pages: 320-323

Type: Article

DOI: 10.1016/j.oftal.2013.06.012 DIALNET GOOGLE SCHOLAR


Case report A 17 year-old male patient, who since 2000 has referred to a progressive bilateral decrease in visual acuity. A «bicycle wheel» macula pattern was observed in his retina. The electroretinogram showed a decrease in the b-wave amplitude. The visual evoked potentials were normal. Optical coherence tomography showed bilateral macular edema. All this supported the diagnosis of X-linked retinoschisis. Discussion Genetic counseling was given and the pattern of X-linked inheritance was explained. A significant improvement of the macular thickness was observed after treatment with topical dorzolamide and oral acetazolamide.