Data for "The glucocorticoid receptor potentiates aldosterone-induced transcription by the mineralocorticoid receptor"

  1. Johnson, Thomas A 1
  2. Fettweis, Gregory 1
  3. Wagh, Kaustubh 12
  4. Ceacero-Heras, Diego 3
  5. Krishnamurthy, Manan 1
  6. Sánchez de Medina, Fermin 4
  7. Martínez-Agustín, Olga 3
  8. Upadhyaya, Arpita 25
  9. Hager, Gordon L 1
  10. Alvarez de la Rosa, Diego 16
  1. 1 Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
  2. 2 Department of Physics, University of Maryland, College Park, MD, USA
  3. 3 Department of Biochemistry and Molecular Biology 2, CIBERehd, School of Pharmacy, Instituto de Investigación Biosanitaria ibs.GRANADA, Instituto de Nutrición y Tecnología de los Alimentos José Mataix, University of Granada, 18071 Granada, Spain
  4. 4 Department of Pharmacology, CIBERehd, School of Pharmacy, Instituto de Investigación Biosanitaria ibs.GRANADA, University of Granada, 18071 Granada, Spain
  5. 5 Institute for Physical Science and Technology, University of Maryland, College Park, MD, USA
  6. 6 Departamento de Ciencias Médicas Básicas and Instituto de Tecnologías Biomédicas, Universidad de La Laguna, Campus de Ciencias de la Salud sn, 38200 San Cristóbal de La Laguna, Spain
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Editor: Zenodo

Year of publication: 2024

Type: Dataset

DOI: 10.5281/ZENODO.12570960 lock_openOpen access editor

Abstract

This deposit contains all the single-molecule trajectories reported in "The Glucocorticoid Receptor is Required for Efficient Aldosterone-Induced Transcription by the Mineralocorticoid Receptor". To access the tracks, open the mat file in MATLAB. This contains a MATLAB table with the following fields: summary_table.cell_protein{i} identifies the ith dataset i.e. cell line + protein + treatment. summary_table.X{i}{j} is an Nx2 array of x and y coordinates (in microns) for track j in condition i. N is the number of localizations in that track. Time interval between localizations is 200 ms. Details on data acquisition and tracking parameters can be found in the associated manuscript.