Publications (16) David Alexander Forsyth Gillespie publications

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2022

  1. DNA damage response proteins in canine cancer as potential research targets in comparative oncology

    Veterinary and Comparative Oncology, Vol. 20, Núm. 2, pp. 347-361

2021

  1. The Nucleocapsid protein triggers the main humoral immune response in COVID-19 patients

    Biochemical and Biophysical Research Communications, Vol. 543, pp. 45-49

2019

  1. Claspin – checkpoint adaptor and DNA replication factor

    FEBS Journal, Vol. 286, Núm. 3, pp. 441-455

2018

  1. AKT overactivation can suppress DNA repair via p70S6 kinase-dependent downregulation of MRE11

    Oncogene, Vol. 37, Núm. 4, pp. 427-438

  2. Chk1 KA1 domain auto-phosphorylation stimulates biological activity and is linked to rapid proteasomal degradation

    Scientific Reports, Vol. 8, Núm. 1

  3. Targeting CHK1 for Cancer Therapy: Rationale, Progress and Prospects

    Cancer Drug Discovery and Development (Humana Press Inc.), pp. 209-240

2017

  1. PERK inhibits DNA replication during the Unfolded Protein Response via Claspin and Chk1

    Oncogene, Vol. 36, Núm. 5, pp. 678-686

2016

  1. Autophagy is critically required for DNA repair by homologous recombination

    Molecular and Cellular Oncology, Vol. 3, Núm. 1

2015

  1. DNA damage control: Regulation and functions of checkpoint kinase 1

    FEBS Journal, Vol. 282, Núm. 19, pp. 3681-3692

  2. KA1-targeted regulatory domain mutations activate Chk1 in the absence of DNA damage

    Scientific Reports, Vol. 5

  3. Loss of autophagy causes a synthetic lethal deficiency in DNA repair

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Núm. 3, pp. 773-778

  4. PARP inhibitor olaparib increases the oncolytic activity of dl922-947 in invitro and invivo model of anaplastic thyroid carcinoma

    Molecular Oncology, Vol. 9, Núm. 1, pp. 78-92

2014

  1. Cancer therapy: Targeting the poison within

    Cell Cycle

2013

  1. Chk1 is essential for the development of murine epidermal melanocytes

    Pigment Cell and Melanoma Research, Vol. 26, Núm. 4, pp. 580-585

  2. Fascin 1 is transiently expressed in mouse melanoblasts during development and promotes migration and proliferation

    Development (Cambridge), Vol. 140, Núm. 10, pp. 2203-2211

  3. Ionizing radiation enhances dl922-947-mediated cell death of anaplastic thyroid carcinoma cells

    Endocrine-Related Cancer, Vol. 20, Núm. 5, pp. 633-647