Publicacións (16) Publicacións de David Alexander Forsyth Gillespie

2022

  1. DNA damage response proteins in canine cancer as potential research targets in comparative oncology

    Veterinary and Comparative Oncology, Vol. 20, Núm. 2, pp. 347-361

2021

  1. The Nucleocapsid protein triggers the main humoral immune response in COVID-19 patients

    Biochemical and Biophysical Research Communications, Vol. 543, pp. 45-49

2019

  1. Claspin – checkpoint adaptor and DNA replication factor

    FEBS Journal, Vol. 286, Núm. 3, pp. 441-455

2018

  1. AKT overactivation can suppress DNA repair via p70S6 kinase-dependent downregulation of MRE11

    Oncogene, Vol. 37, Núm. 4, pp. 427-438

  2. Chk1 KA1 domain auto-phosphorylation stimulates biological activity and is linked to rapid proteasomal degradation

    Scientific Reports, Vol. 8, Núm. 1

  3. Targeting CHK1 for Cancer Therapy: Rationale, Progress and Prospects

    Cancer Drug Discovery and Development (Humana Press Inc.), pp. 209-240

2017

  1. PERK inhibits DNA replication during the Unfolded Protein Response via Claspin and Chk1

    Oncogene, Vol. 36, Núm. 5, pp. 678-686

2016

  1. Autophagy is critically required for DNA repair by homologous recombination

    Molecular and Cellular Oncology, Vol. 3, Núm. 1

2015

  1. DNA damage control: Regulation and functions of checkpoint kinase 1

    FEBS Journal, Vol. 282, Núm. 19, pp. 3681-3692

  2. KA1-targeted regulatory domain mutations activate Chk1 in the absence of DNA damage

    Scientific Reports, Vol. 5

  3. Loss of autophagy causes a synthetic lethal deficiency in DNA repair

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Núm. 3, pp. 773-778

  4. PARP inhibitor olaparib increases the oncolytic activity of dl922-947 in invitro and invivo model of anaplastic thyroid carcinoma

    Molecular Oncology, Vol. 9, Núm. 1, pp. 78-92

2014

  1. Cancer therapy: Targeting the poison within

    Cell Cycle

2013

  1. Chk1 is essential for the development of murine epidermal melanocytes

    Pigment Cell and Melanoma Research, Vol. 26, Núm. 4, pp. 580-585

  2. Fascin 1 is transiently expressed in mouse melanoblasts during development and promotes migration and proliferation

    Development (Cambridge), Vol. 140, Núm. 10, pp. 2203-2211

  3. Ionizing radiation enhances dl922-947-mediated cell death of anaplastic thyroid carcinoma cells

    Endocrine-Related Cancer, Vol. 20, Núm. 5, pp. 633-647