Publikationen in Zusammenarbeit mit Forschern von Instituto de Parasitología y Biomedicina López Neyra (18)

2016

  1. Optimization by Molecular Fine Tuning of Dihydro-β-agarofuran Sesquiterpenoids as Reversers of P-Glycoprotein-Mediated Multidrug Resistance

    Journal of Medicinal Chemistry, Vol. 59, Núm. 5, pp. 1880-1890

2015

  1. Restoration of chemosensitivity in P-glycoprotein-dependent multidrug-resistant cells by dihydro-β-agarofuran sesquiterpenes from Celastrus vulcanicola

    Journal of Natural Products, Vol. 78, Núm. 4, pp. 736-745

2011

  1. Leishmanicidal and reversal multidrug resistance constituents from Aeonium lindleyi

    Planta Medica, Vol. 77, Núm. 1, pp. 77-80

  2. Overcoming human P-glycoprotein-dependent multidrug resistance with novel dihydro-β-agarofuran sesquiterpenes

    European Journal of Medicinal Chemistry, Vol. 46, Núm. 10, pp. 4915-4923

  3. Terpenoids from maytenus species and assessment of their reversal activity against a multidrug-resistant leishmania tropica line

    Chemistry and Biodiversity, Vol. 8, Núm. 12, pp. 2291-2298

2009

  1. Novel dihydro-β-agarofuran sesquiterpenes as potent modulators of human P-glycoprotein dependent multidrug resistance

    Organic and Biomolecular Chemistry, Vol. 7, Núm. 24, pp. 5166-5172

2007

  1. Biological evaluation, structure-activity relationships, and three-dimensional quantitative structure-activity relationship studies of dihydro-β-agarofuran sesquiterpenes as modulators of P-glycoprotein- dependent multidrug resistance

    Journal of Medicinal Chemistry, Vol. 50, Núm. 20, pp. 4808-4817

  2. Leishmanicidal constituents from the leaves of Piper rusbyi

    Planta Medica, Vol. 73, Núm. 3, pp. 206-211

2006

  1. Insights into the molecular mechanism of action of Celastraceae sesquiterpenes as specific, non-transported inhibitors of human P-glycoprotein

    Biochimica et Biophysica Acta - Biomembranes, Vol. 1758, Núm. 1, pp. 98-110

2005

  1. Dihidro-β-agarofuran sesquiterpenes: A new class of reversal agents of the multidrug resistance phenotype mediated by P-glycoprotein in the protozoan parasite Leishmania

    Current Pharmaceutical Design, Vol. 11, Núm. 24, pp. 3125-3159

  2. Functional expression of a multidrug P-glycoprotein transporter of Leishmania

    Biochemical and Biophysical Research Communications, Vol. 329, Núm. 2, pp. 502-507

  3. Reversion of human Pgp-dependent multidrug resistance by new sesquiterpenes from Zinowiewia costaricensis

    Journal of Medicinal Chemistry, Vol. 48, Núm. 13, pp. 4266-4275

2004

  1. Celastraceae sesquiterpenes as a new class of modulators that bind specifically to human P-glycoprotein and reverse cellular multidrug resistance

    Cancer Research, Vol. 64, Núm. 19, pp. 7130-7138

  2. SAR Studies of Dihydro-β-agarofuran Sesquiterpenes as Inhibitors of the Multidrug-Resistance Phenotype in a Leishmania tropica Line Overexpressing a P-Glycoprotein-Like Transporter

    Journal of Medicinal Chemistry, Vol. 47, Núm. 3, pp. 576-587

2003

  1. Absolute configuration and complete assignment of 13 C NMR data for new sesquiterpenes from Maytenus chiapensis

    Journal of Natural Products, Vol. 66, Núm. 4, pp. 572-574

2001

  1. Alkyl-lysophospholipid resistance in multidrug-resistant Leishmania tropica and chemosensitization by a novel P-glycoprotein-like transporter modulator

    Antimicrobial Agents and Chemotherapy, Vol. 45, Núm. 9, pp. 2468-2474

  2. Chemosensitization of a multidrug-resistant Leishmania tropica line by new sesquiterpenes from Maytenus magellanica and Maytenus chubutensis

    Journal of Medicinal Chemistry, Vol. 44, Núm. 26, pp. 4668-4676

1999

  1. New natural sesquiterpenes as modulators of daunomycin resistance in a multidrug-resistant Leishmania tropica line

    Journal of Medicinal Chemistry, Vol. 42, Núm. 21, pp. 4388-4393