Ignacio Antonio
Jiménez Díaz
Profesor Titular Universidad
![Foto de Ignacio Antonio](/img/nophoto.png)
![Foto de Instituto de Parasitología y Biomedicina López Neyra](/img/noimage_org.png)
Instituto de Parasitología y Biomedicina López Neyra
Armilla, EspañaInstituto de Parasitología y Biomedicina López Neyra -ko ikertzaileekin lankidetzan egindako argitalpenak (18)
2016
-
Optimization by Molecular Fine Tuning of Dihydro-β-agarofuran Sesquiterpenoids as Reversers of P-Glycoprotein-Mediated Multidrug Resistance
Journal of Medicinal Chemistry, Vol. 59, Núm. 5, pp. 1880-1890
2015
-
Restoration of chemosensitivity in P-glycoprotein-dependent multidrug-resistant cells by dihydro-β-agarofuran sesquiterpenes from Celastrus vulcanicola
Journal of Natural Products, Vol. 78, Núm. 4, pp. 736-745
2011
-
Leishmanicidal and reversal multidrug resistance constituents from Aeonium lindleyi
Planta Medica, Vol. 77, Núm. 1, pp. 77-80
-
Overcoming human P-glycoprotein-dependent multidrug resistance with novel dihydro-β-agarofuran sesquiterpenes
European Journal of Medicinal Chemistry, Vol. 46, Núm. 10, pp. 4915-4923
-
Terpenoids from maytenus species and assessment of their reversal activity against a multidrug-resistant leishmania tropica line
Chemistry and Biodiversity, Vol. 8, Núm. 12, pp. 2291-2298
2009
-
Novel dihydro-β-agarofuran sesquiterpenes as potent modulators of human P-glycoprotein dependent multidrug resistance
Organic and Biomolecular Chemistry, Vol. 7, Núm. 24, pp. 5166-5172
2007
-
Biological evaluation, structure-activity relationships, and three-dimensional quantitative structure-activity relationship studies of dihydro-β-agarofuran sesquiterpenes as modulators of P-glycoprotein- dependent multidrug resistance
Journal of Medicinal Chemistry, Vol. 50, Núm. 20, pp. 4808-4817
-
Leishmanicidal constituents from the leaves of Piper rusbyi
Planta Medica, Vol. 73, Núm. 3, pp. 206-211
2006
-
Insights into the molecular mechanism of action of Celastraceae sesquiterpenes as specific, non-transported inhibitors of human P-glycoprotein
Biochimica et Biophysica Acta - Biomembranes, Vol. 1758, Núm. 1, pp. 98-110
2005
-
Dihidro-β-agarofuran sesquiterpenes: A new class of reversal agents of the multidrug resistance phenotype mediated by P-glycoprotein in the protozoan parasite Leishmania
Current Pharmaceutical Design, Vol. 11, Núm. 24, pp. 3125-3159
-
Functional expression of a multidrug P-glycoprotein transporter of Leishmania
Biochemical and Biophysical Research Communications, Vol. 329, Núm. 2, pp. 502-507
-
Reversion of human Pgp-dependent multidrug resistance by new sesquiterpenes from Zinowiewia costaricensis
Journal of Medicinal Chemistry, Vol. 48, Núm. 13, pp. 4266-4275
2004
-
Celastraceae sesquiterpenes as a new class of modulators that bind specifically to human P-glycoprotein and reverse cellular multidrug resistance
Cancer Research, Vol. 64, Núm. 19, pp. 7130-7138
-
SAR Studies of Dihydro-β-agarofuran Sesquiterpenes as Inhibitors of the Multidrug-Resistance Phenotype in a Leishmania tropica Line Overexpressing a P-Glycoprotein-Like Transporter
Journal of Medicinal Chemistry, Vol. 47, Núm. 3, pp. 576-587
2003
-
Absolute configuration and complete assignment of 13 C NMR data for new sesquiterpenes from Maytenus chiapensis
Journal of Natural Products, Vol. 66, Núm. 4, pp. 572-574
2001
-
Alkyl-lysophospholipid resistance in multidrug-resistant Leishmania tropica and chemosensitization by a novel P-glycoprotein-like transporter modulator
Antimicrobial Agents and Chemotherapy, Vol. 45, Núm. 9, pp. 2468-2474
-
Chemosensitization of a multidrug-resistant Leishmania tropica line by new sesquiterpenes from Maytenus magellanica and Maytenus chubutensis
Journal of Medicinal Chemistry, Vol. 44, Núm. 26, pp. 4668-4676
1999
-
New natural sesquiterpenes as modulators of daunomycin resistance in a multidrug-resistant Leishmania tropica line
Journal of Medicinal Chemistry, Vol. 42, Núm. 21, pp. 4388-4393