Publicaciones en colaboración con investigadores/as de Instituto Canario de Investigación del Cáncer (60)

2022

  1. Guanidine Derivatives Containing the Chalcone Skeleton Are Potent Antiproliferative Compounds against Human Leukemia Cells

    International journal of molecular sciences, Vol. 23, Núm. 24

  2. Structure-activity relationships reveal a 2-furoyloxychalcone as a potent cytotoxic and apoptosis inducer for human U-937 and HL-60 leukaemia cells

    Bioorganic Chemistry, Vol. 127

2017

  1. Bioactive diterpenoids from Celastraceae species

    Phytochemistry Reviews, Vol. 16, Núm. 5, pp. 861-881

  2. CM363, a novel naphthoquinone derivative which acts as multikinase modulator and overcomes imatinib resistance in chronic myelogenous leukemia

    Oncotarget, Vol. 8, Núm. 18, pp. 29679-29698

  3. Structure-based design, synthesis, and biological evaluation of withaferin A-analogues as potent apoptotic inducers

    European Journal of Medicinal Chemistry, Vol. 140, pp. 52-64

2016

  1. Absolute Configuration of Dihydro-β-agarofuran Sesquiterpenes from Maytenus jelskii and Their Potential Antitumor-Promoting Effects

    Journal of Natural Products, Vol. 79, Núm. 9, pp. 2324-2331

  2. Optimization by Molecular Fine Tuning of Dihydro-β-agarofuran Sesquiterpenoids as Reversers of P-Glycoprotein-Mediated Multidrug Resistance

    Journal of Medicinal Chemistry, Vol. 59, Núm. 5, pp. 1880-1890

2014

  1. A new family of choline kinase inhibitors with antiproliferative and antitumor activity derived from natural products

    Clinical and Translational Oncology, Vol. 17, Núm. 1, pp. 74-84

  2. Yeast cytotoxic sensitivity to the antitumour agent β-lapachone depends mainly on oxidative stress and is largely independent of microtubule- or topoisomerase-mediated DNA damage

    Biochemical Pharmacology, Vol. 92, Núm. 2, pp. 206-219

2013

  1. Achyrofuran is an antibacterial agent capable of killing methicillin-resistant vancomycin-intermediate Staphylococcus aureus in the nanomolar range

    Phytomedicine, Vol. 20, Núm. 2, pp. 133-138

  2. Multicomponent synthesis of antibacterial dihydropyridin and dihydropyran embelin derivatives

    Journal of Organic Chemistry, Vol. 78, Núm. 16, pp. 7977-7985

  3. Preparation and antimalarial activity of semisynthetic lycorenine derivatives

    European Journal of Medicinal Chemistry, Vol. 63, pp. 722-730

  4. Synthesis and cytotoxic activity of metallic complexes of lawsone

    Bioorganic and Medicinal Chemistry, Vol. 21, Núm. 9, pp. 2471-2477

  5. Synthesis and study of antiproliferative, antitopoisomerase II, DNA-intercalating and DNA-damaging activities of arylnaphthalimides

    Bioorganic and Medicinal Chemistry, Vol. 21, Núm. 21, pp. 6484-6495

2012

  1. Antiproliferative activity of withanolide derivatives from Jaborosa cabrerae and Jaborosa reflexa. Chemotaxonomic considerations

    Phytochemistry, Vol. 76, pp. 150-157

  2. Labdanolic acid methyl ester (LAME) exerts anti-inflammatory effects through inhibition of TAK-1 activation

    Toxicology and Applied Pharmacology, Vol. 258, Núm. 1, pp. 109-117

  3. Synthesis and anti-HIV activity of lupane and olean-18-ene derivatives. Absolute configuration of 19,20-epoxylupanes by VCD

    Journal of Natural Products, Vol. 75, Núm. 4, pp. 669-676

  4. Synthesis and antimalarial activity of new haemanthamine-type derivatives

    Bioorganic and Medicinal Chemistry, Vol. 20, Núm. 18, pp. 5464-5472

  5. Unexpected domino synthesis of complex angular naphthoimidazoles

    European Journal of Organic Chemistry, pp. 5757-5766

2011

  1. Benzodihydrofurans from Cyperus teneriffae

    Journal of Natural Products, Vol. 74, Núm. 5, pp. 1061-1065