Publicaciones en colaboración con investigadores/as de Instituto Canario de Investigación del Cáncer (33)

2014

  1. Yeast cytotoxic sensitivity to the antitumour agent β-lapachone depends mainly on oxidative stress and is largely independent of microtubule- or topoisomerase-mediated DNA damage

    Biochemical Pharmacology, Vol. 92, Núm. 2, pp. 206-219

2013

  1. Achyrofuran is an antibacterial agent capable of killing methicillin-resistant vancomycin-intermediate Staphylococcus aureus in the nanomolar range

    Phytomedicine, Vol. 20, Núm. 2, pp. 133-138

  2. Multicomponent synthesis of antibacterial dihydropyridin and dihydropyran embelin derivatives

    Journal of Organic Chemistry, Vol. 78, Núm. 16, pp. 7977-7985

  3. Synthesis and study of antiproliferative, antitopoisomerase II, DNA-intercalating and DNA-damaging activities of arylnaphthalimides

    Bioorganic and Medicinal Chemistry, Vol. 21, Núm. 21, pp. 6484-6495

2012

  1. Antiproliferative activity of withanolide derivatives from Jaborosa cabrerae and Jaborosa reflexa. Chemotaxonomic considerations

    Phytochemistry, Vol. 76, pp. 150-157

2011

  1. Comparative analysis of the ERα/ERβ ratio and neurotensin and its high-affinity receptor in myometrium, uterine leiomyoma, atypical leiomyoma, and leiomyosarcoma

    International Journal of Gynecological Pathology, Vol. 30, Núm. 4, pp. 354-363

  2. Neurotensina y otros Péptidos reguladores en el desarrollo hipofisario humano y en adenomas hipofisarios

    BioCancer Research Journal, Vol. 5, pp. 161-170

2010

  1. Antiproliferative activity of novel benzo[b][1,6]naphthyridines in human solid tumor cell lines

    Bioorganic and Medicinal Chemistry Letters, Vol. 20, Núm. 5, pp. 1504-1506

  2. Antiproliferative activity of synthetic naphthoquinones related to lapachol. First synthesis of 5-hydroxylapachol

    Bioorganic and Medicinal Chemistry, Vol. 18, Núm. 7, pp. 2621-2630

  3. Enhancement of antiproliferative activity by molecular simplification of catalpol

    Bioorganic and Medicinal Chemistry, Vol. 18, Núm. 7, pp. 2515-2523

  4. Mitotic arrest induced by a novel family of DNA topoisomerase II inhibitors

    Journal of Medicinal Chemistry, Vol. 53, Núm. 9, pp. 3835-3839

  5. Neurotensin and neurotensin receptor 1 expression in human myometrium and uterine leiomyomas

    Biology of Reproduction, Vol. 83, Núm. 4, pp. 641-647

2009

  1. Synthesis and antiproliferative activity of 2,4-disubstituted 6-aryl-7H-pyrrolo[3,2-d]pyrimidin-7-one 5-oxides

    Bioorganic and Medicinal Chemistry, Vol. 17, Núm. 14, pp. 4955-4960

  2. Tessaric acid derivatives induce G2/M cell cycle arrest in human solid tumor cell lines

    Bioorganic and Medicinal Chemistry, Vol. 17, Núm. 17, pp. 6251-6256

2008

  1. Design and synthesis of a novel series of pyranonaphthoquinones as topoisomerase II catalytic inhibitors

    Journal of Medicinal Chemistry, Vol. 51, Núm. 21, pp. 6761-6772

  2. Expression of neurotensin and its receptors in pituitary adenomas

    Journal of Neuroendocrinology, Vol. 20, Núm. 9, pp. 1052-1057

  3. β′-Hydroxy-α,β-unsaturated ketones: A new pharmacophore for the design of anticancer drugs. Part 2

    ChemMedChem, Vol. 3, Núm. 11, pp. 1740-1747

  4. γ-Lactones α,β- and β,γ-fused to carbocycles as novel antiproliferative drugs

    Bioorganic and Medicinal Chemistry Letters, Vol. 18, Núm. 19, pp. 5171-5173

2007

  1. Antiproliferative activity of 2-alkyl-4-halopiperidines and 2-alkyl-4-halo-1,2,5,6-tetrahydropyridines in solid tumor cell lines

    Bioorganic and Medicinal Chemistry Letters, Vol. 17, Núm. 10, pp. 2681-2684

  2. Antiproliferative activity of 4-chloro-5,6-dihydro-2H-pyrans. Part 2: Enhancement of drug cytotoxicity

    Bioorganic and Medicinal Chemistry Letters, Vol. 17, Núm. 11, pp. 3087-3090