Retinopatía MEKCasos clínicos

  1. P.Rocha Cabrera 1
  2. E.Quijada Fumero 1
  3. M.J.Losada Castillo 1
  4. J.A.Abreu Reyes 1
  5. J.Lorenzo Morales 1
  1. 1 Servicio de Oftalmología, Hospital Universitario de Canarias, La Laguna (Tenerife), España
Revista:
Archivos de la Sociedad Española de Oftalmologia

ISSN: 0365-6691

Any de publicació: 2018

Volum: 93

Número: 1

Pàgines: 42-46

Tipus: Article

DOI: 10.1016/J.OFTAL.2017.03.005 DIALNET GOOGLE SCHOLAR

Altres publicacions en: Archivos de la Sociedad Española de Oftalmologia

Resum

Case reports: Three clinical cases are presented of MEK retinopathy associated with the combination of cobimetinib and vemurafenib characterised by alteration of the retinal pigment epithelium and neurosensory detachment. Two of the cases conserved the vision of the unit, and the third developed a large bilateral neurosensory detachment with final visual acuity of 0.6 for the right eye and 0.1 for the left one. Discussion: The new therapeutic strategies against metastatic cutaneous melanoma condition the appearance of alterations of the pigmentary epithelium of the retina with serous detachments, leading to close monitoring with macular optical coherence tomography.

Fuente de los datos: Dialnet