Retinopatía MEKCasos clínicos

  1. Pedro Rocha Cabrera 1
  2. E. Quijada Fumero 1
  3. M. J. Losada Castillo 1
  4. J. A. Abreu Reyes 1
  5. Jacob Lorenzo Morales 1
  1. 1 Hospital Universitario de Canarias

    Hospital Universitario de Canarias

    San Cristóbal de La Laguna, España

    GRID grid.411220.4

Archivos de la Sociedad Española de Oftalmologia

ISSN: 0365-6691

Year of publication: 2018

Volume: 93

Issue: 1

Pages: 42-46

Type: Article

Export: RIS
DOI: 10.1016/j.oftal.2017.03.005 DIALNET GOOGLE SCHOLAR


Cited by

  • Scopus Cited by: 1 (24-10-2021)

SCImago Journal Rank

  • Year 2018
  • SJR Journal Impact: 0.23
  • Best Quartile: Q3
  • Area: Ophthalmology Quartile: Q3 Rank in area: 90/126


  • Year 2018
  • CiteScore of the Journal : 0.6
  • Area: Ophthalmology Percentile: 22


Case reports: Three clinical cases are presented of MEK retinopathy associated with the combination of cobimetinib and vemurafenib characterised by alteration of the retinal pigment epithelium and neurosensory detachment. Two of the cases conserved the vision of the unit, and the third developed a large bilateral neurosensory detachment with final visual acuity of 0.6 for the right eye and 0.1 for the left one. Discussion: The new therapeutic strategies against metastatic cutaneous melanoma condition the appearance of alterations of the pigmentary epithelium of the retina with serous detachments, leading to close monitoring with macular optical coherence tomography.