Retinopatía MEKCasos clínicos
- P.Rocha Cabrera 1
- E.Quijada Fumero 1
- M.J.Losada Castillo 1
- J.A.Abreu Reyes 1
- J.Lorenzo Morales 1
- 1 Servicio de Oftalmología, Hospital Universitario de Canarias, La Laguna (Tenerife), España
ISSN: 0365-6691
Année de publication: 2018
Volumen: 93
Número: 1
Pages: 42-46
Type: Article
D'autres publications dans: Archivos de la Sociedad Española de Oftalmologia
Objectifs de Développement Durable
Résumé
Case reports: Three clinical cases are presented of MEK retinopathy associated with the combination of cobimetinib and vemurafenib characterised by alteration of the retinal pigment epithelium and neurosensory detachment. Two of the cases conserved the vision of the unit, and the third developed a large bilateral neurosensory detachment with final visual acuity of 0.6 for the right eye and 0.1 for the left one. Discussion: The new therapeutic strategies against metastatic cutaneous melanoma condition the appearance of alterations of the pigmentary epithelium of the retina with serous detachments, leading to close monitoring with macular optical coherence tomography.